Phenethyl alcohol | CAS:60-12-8 | Manufacturer ChemFaces

Phenethyl alcohol

Citing Use of our Products

How to Order

Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: info@chemfaces.com

Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Fax: (0086)-27-84254680
E-mail: manager@chemfaces.com
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC

Delivery time

Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal & Western Union

* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $7.0 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

Featured Products

More...

6',7'-Dihydroxybergamottin

Catalog No: CFN98307
CAS No: 264234-05-1
Price: $318/10mg

Hesperetin

Catalog No: CFN98842
CAS No: 520-33-2
Price: $40/20mg

Acetylshikonin

Catalog No: CFN90308
CAS No: 54984-93-9
Price: $338/20mg

Syringin

Catalog No: CFN99282
CAS No: 118-34-3
Price: $80/20mg

Apterin

Catalog No: CFN95005
CAS No: 53947-89-0
Price: $388/10mg

Sibiricose A5

Catalog No: CFN90645
CAS No: 107912-97-0
Price: $138/20mg

Cyanidin-3-O-glucoside chloride

Catalog No: CFN99740
CAS No: 7084-24-4
Price: $118/20mg

Description:

Phenethyl alcohol shows effect on breakdown of the cell membrane. Phenethyl alcohol shows selective inhibitory effects on gram-negative bacteria , at a concentration of 0.25%, phenethyl alcohol was bacteriostatic for gram-negative bacteria; gram-positive cells were unaffected.

Targets:

Antifection

In vitro:

Journal of Bacteriology, 1967, 93(2):560.

Mechanism of action of phenethyl alcohol: breakdown of the cellular permeability barrier.[Reference: WebLink]

METHODS AND RESULTS:
Phenethyl alcohol (PEA) caused Escherichia coli to take up greatly increased amounts of acriflavine, a compound to which healthy growing cells are impermeable. PEA also caused an increased rate of efflux (leakage) of cellular potassium under conditions which do not greatly alter the influx of potassium via the energy-dependent potassium pump.
CONCLUSIONS:
We therefore propose that the primary effect of PEA is a limited breakdown of the cell membrane. The inhibition of deoxyribonucleic acid synthesis and other cellular functions would then be secondary consequences of the alteration in the membrane structure.

Journal of Bacteriology, 1962, 83(4):738.

Selective and reversible inhibition of the synthesis of bacterial deoxyribonucleic acid by phenethyl alcohol.[Reference: WebLink]

METHODS AND RESULTS:
The selective inhibitory effects of Phenethyl alcohol on gram-negative bacteria were confirmed with a variety of species. At a concentration of 0.25%, Phenethyl alcohol was bacteriostatic for gram-negative bacteria; gram-positive cells were unaffected. Pseudomonas fluorescens required higher concentrations of the compound for inhibition than did the other gram-negative bacteria, and the gram-positive, acid-fast mycobacteria resembled the majority of gram-negative bacteria in sensitivity. In the presence of Phenethyl alcohol, gram-negative cells formed long filaments. There was no net synthesis of deoxyribonucleic acid (DNA) in such cells, whereas protein and ribonucleic acid (RNA) syntheses were unaffected. Upon removal of Phenethyl alcohol, multiplication of the cells immediately ensued, with concomitant DNA synthesis.
CONCLUSIONS:
Yeast extract stimulated both RNA and protein synthesis in Phenethyl alcohol-treated Escherichia coli, but no detectable stimulation of DNA synthesis occurred under these conditions.

Journal of Bacteriology, 1972, 109(1):162.

Effects of phenethyl alcohol on phospholipid metabolism in Escherichia coli.[Reference: WebLink]

METHODS AND RESULTS:
The incorporation of labeled precursors into the deoxyribonucleic acid, ribonucleic acid (RNA), proteins, and phospholipids of Escherichia coli cultured in the presence of Phenethyl alcohol (PEA) was determined. PEA inhibited the uptake of labeled uracil to the same extent in cells exhibiting relaxed and stringent control of RNA synthesis. This indicates that PEA does not primarily affect amino acid synthesis or activation. Uptake of labeled acetate into the phospholipid fraction was more sensitive to inhibition by low concentrations of PEA than was the uptake of labeled precursors into the macromolecules. Thymine starvation or the addition of nalidixic acid (10 mug/ml) had no effect on acetate incorporation. Chloramphenicol (25 mug/ml) was a much less effective inhibitor of acetate incorporation than was PEA. The distribution of labeled acetate incorporated into phospholipids was markedly affected by the presence of PEA. The uptake of acetate into phosphatidylethanolamine and phosphatidylglycerol was inhibited, whereas the uptake of acetate into the cardiolipin fraction was unaffected.
CONCLUSIONS:
Since acetate incorporation into phospholipid was quite sensitive to PEA, we suggest that the PEA-sensitive component required for the initiation of replication may be a phospholipid(s).

Phenethyl alcohol Description

Source:	The roots of Rehmannia glutinosa var. purpurea
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

CAS No.	60-12-8	Price	$30 / 20mg
Catalog No.	CFN70163	Purity	>=98%
Molecular Weight	122.1	Type of Compound	Phenols
Formula	C₈H₁₀O	Physical Description	Oil
Download	COA MSDS	Similar structural	Comparison

Product Name	Phenethyl alcohol
CAS No.:	60-12-8
Catalog No.:	CFN70163
Molecular Formula:	C₈H₁₀O
Molecular Weight:	122.1 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Oil
Targets:	Antifection
Source:	The roots of Rehmannia glutinosa var. purpurea
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:	$30 / 20mg
Download:	COA MSDS
Similar structural:	Comparison

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Phenols Compound Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	8.19 mL	40.95 mL	81.9001 mL	163.8002 mL	204.7502 mL
5 mM	1.638 mL	8.19 mL	16.38 mL	32.76 mL	40.95 mL
10 mM	0.819 mL	4.095 mL	8.19 mL	16.38 mL	20.475 mL
50 mM	0.1638 mL	0.819 mL	1.638 mL	3.276 mL	4.095 mL
100 mM	0.0819 mL	0.4095 mL	0.819 mL	1.638 mL	2.0475 mL

CFN89456	Carmichaenine B	2065228-60-4	439.54	C₂₃H₃₇NO₇
CFN89407	Erythrocentaurin	50276-98-7	176.16	C₁₀H₈O₃
CFN90531	3-O-Acetyl-11-keto-beta-boswellic acid	67416-61-9	512.72	C₃₂H₄₈O₅
CFN90581	Columbamine	3621-36-1	338.38	C₂₀H₂₀NO₄