ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
3. Inhibitors
Citing Use of our Products
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Tel: (0086)-27-84237683
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / Inquiry |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Phytomedicine.2020, 79, 153351Food Chem.2020, 313:126079Korean Journal of Pharmacognosy...2018...New Zealand J. Forestry Sci.2014, 44:17Evid Based Complement Alternat Me...2020...Chem Biol Interact.2019, 298:1-7LWT2021, 147:111620.ACS Synth Biol.2020, 9(9):2282-2290.
Cardiovasc Toxicol.2019, 19(4):297-305Genes (Basel).2021, 12(7):1024.BMC Complement Altern Med.2016, 16:213Journal of Third Military Medical...2018...Molecules.2020, 25(9):2111.Food Chem.2019, 274:345-350Food Science and Biotechnology...2015...Research on Crops.2017, 18(3):569
J Sep Sci.2020, 201901140Industrial Crops and Products...2017...Molecules.2020 ,25(16):3697.International J of Green Pharmacy...2019...Pharmacol Res.2020, 161:105205.Plant Sci.2020, 301:110656.Front Pharmacol.2019, 10:1355
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Our products had been exported to the following research institutions and universities, And still growing.
Lodz University of Technology (Poland)Universidade do Porto (Portugal)Colorado State University (USA)National Research Council of Ca... (Canada)
Kitasato University (Japan)University of Canterbury (New Zealand)Max-Planck-Insitut (Germany)Gyeongsang National University (Korea)
Northeast Normal University Cha... (China)Universidade Federal de Pernamb... (Brazil)Sri Sai Aditya Institute of Pha... (India)
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Phoyunnanin C
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
J of App. Res. on Med&Aromatic Plants2020, 100291.Evid Based Complement Alternat Med.2021, 2021:6687513.Food Analytical Methods2020, 1-10Phytomedicine.2015, 22(11):1027-36Anal Chim Acta.2021, 1180:338874.Pharmaceuticals (Basel).2021, 14(3):260.J of the Society of Cosmetic Scientists of Korea2018, 44(4):407-417Plants (Basel).2021, 10(2):278. Cardiovasc Toxicol.2019, 19(4):297-305Processes2021, 9(1), 153;
Related Screening Libraries
| Description: |
Phoyunnanin C shows cytotoxic activity. It also shows moderate activity against the Herpes simplex virus. |
| Targets: |
HSV |
| In vitro: |
| Nat Prod Commun. 2014 Jun;9(6):825-7. | | Chemical constituents of Dendrobium venustum and their antimalarial and anti-herpetic properties.[Pubmed: 25115090 ] |
METHODS AND RESULTS:
A MeOH extract from the whole plant Dendrobium venustum exhibited significant antimalarial and anti-herpetic activities. Bioassay-guided isolation of the plant extract resulted in the isolation of seven known phenolic compounds. Densiflorol B (3) and phoyunnanin E (6) showed the strongest antimalarial activity and a high selectivity index, whereas gigantol (2), batatasin III (5) and Phoyunnanin C (7) exhibited moderate activity. Compounds 2 and 5 also showed weak activity against the Herpes simplex virus.
CONCLUSIONS:
This study is the first report on the chemical and biological activities of D. venustum. | | J Asian Nat Prod Res. 2013;15(12):1256-64. | | Inhibitory activities on nitric oxide production of stilbenoids from Pholidota yunnanensis.[Pubmed: 24205813] |
METHODS AND RESULTS:
Three new stilbenoids, 1-(4'-hydroxybenzyl)-imbricatin, (E)-4'-hydroxy-2',3,3',5-tetramethoxystilbene, and (E)-3,4'-dihydroxy-2,6-bis(4-hydroxybenzyl)-2',3',5-trimethoxystilbene, together with 15 known stilbene derivatives, were isolated from Pholidota yunnanensis. Their structures were elucidated by spectroscopic methods and by comparison of their NMR data with those of related compounds. Furthermore, the inhibitory activities on nitric oxide (NO) production of the isolated compounds were examined in murine macrophages (RAW 264.7) activated by lipopolysaccharide. The cytotoxicity of 18 compounds was determined by the 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium assay.
CONCLUSIONS:
Among the tested compounds, eight stilbenoids, including three dihydrophenanthrenes, three stilbenes, and one bibenzyl derivative showed inhibitory effects on NO production without cytotoxicity with IC₅₀ values ranging from 4.07 to 7.77 μM, as compared to MG-132, which was used as a positive control (IC₅₀ of 0.10 μM). One dihydrophenanthrene, Phoyunnanin C, showed cytotoxic effects at the test concentrations. |
|
Phoyunnanin C Description
| Source: |
The herbs of Dendrobium nobile Lindl. |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
2.0725 mL |
10.3627 mL |
20.7254 mL |
41.4508 mL |
51.8135 mL |
| 5 mM |
0.4145 mL |
2.0725 mL |
4.1451 mL |
8.2902 mL |
10.3627 mL |
| 10 mM |
0.2073 mL |
1.0363 mL |
2.0725 mL |
4.1451 mL |
5.1813 mL |
| 50 mM |
0.0415 mL |
0.2073 mL |
0.4145 mL |
0.829 mL |
1.0363 mL |
| 100 mM |
0.0207 mL |
0.1036 mL |
0.2073 mL |
0.4145 mL |
0.5181 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
