ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
3. Inhibitors
Yuankanin
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $365.7 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Phytother Res.2022, ptr.7573.Pharm Biol.2021, 59(1):134-145.Mol Med Rep.2014, 9(5):1653-9Applied Biological Chemistry2021, 64(4)Biomolecules.2022, 12(12):1754.Int J Mol Sci.2019, 20(21):E5488J Korean Society of Food Science ...2021...J.of Traditional&Complementary Me...2022...
PLoS One.2018, 13(4):e0195642Biomedicines.2020, 8(11):486.Nutrients.2017, 10(1)Microorganisms.2021, 9(12):2514.Curr Issues Mol Biol....2022...Korean J of Pharmacognosy...2020...Environ Toxicol.2019, 34(4):513-520.Front Pharmacol.2022, 13:883475.
Plant Methods.2017, 13:108J Funct Foods2019, 54:449-456Biofactors.2018, 44(2):168-179Nutr Cancer.2022, 1-13.Front Plant Sci.2018, 9:1424Pol J Microbiol.2021, 70(1):117-130.J Ethnopharmacol.2022, 289:115018.
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Our products had been exported to the following research institutions and universities, And still growing.
Heinrich-Heine-University Düss... (Germany)Korea Food Research Institute(K... (Korea)Sanford Burnham Prebys Medical ... (USA)Kitasato University (Japan)
Julius Kühn-Institut (Germany)Monash University (Australia)Shanghai Institute of Biochemis... (China)Leibniz-Institut für Pflanzenb... (Germany)
Chinese University of Hong Kong (China)Rio de Janeiro State University (Brazil)University of Hull (United Kingdom)
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Yuankanin
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Free Radic Biol Med.2021, 166:104-115.Food Res Int.2019, 123:125-134Phytomedicine.2021, 83:153483. Molecular & Cellular Toxicology2017, 13(3):271-278J Nat Med.2017, 71(2):457-462Korean Herb. Med. Inf.2020, 8(2):243-254.Molecules.2019, 24(23):E4303Antioxidants (Basel).2020, 9(4):284.Anal Bioanal Chem.2018, 410(5):1561-1569Research Square2021, 10.21203.
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
Flavonoids Compound Library |
| Description: |
Reference standards. |
| In vitro: |
| Phytochemistry. 2008 Jan;69(2):541-5. | | Flavones from Struthiola argentea with anthelmintic activity in vitro.[Pubmed: 17923139 ] | Parasitic diseases caused by helminthes lead to significant health hazards to animals resulting in enormous economic impact. While a number of anthelmintics are currently available, all are encountering resistance and ones with a mode of action are needed.
METHODS AND RESULTS:
We report herein bioassay-guided isolation of three anthelmintic flavones 1-3, including the flavone, 5,6,2',5',6'-pentamethoxy-3',4'-methylenedioxyflavone (3) from the methanol extract of Struthiola argentea (Thymelaeaceae). The structure of 3 was elucidated by analysis of its 1D and 2D NMR and MS data. The two major flavones produced by this plant were also isolated and identified as Yuankanin (4) and amentoflavone (5). A number of flavones related to the compounds isolated from S. argentea were acquired and tested to ascertain structure activity relationships. The isolation, structure, anthelmintic activity and structure activity relationships of the flavones are described.
CONCLUSIONS:
Compound 3 exhibited the most potent in vitro activity with 90% inhibition of larval motility at 3.1 microg/mL and compound 15 showed modest in vivo activity. |
|
Yuankanin Description
| Source: |
The herbs of Daphne genkwa |
| Solvent: |
DMSO, Pyridine, Methanol, Ethanol, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
1.7286 mL |
8.643 mL |
17.2861 mL |
34.5722 mL |
43.2152 mL |
| 5 mM |
0.3457 mL |
1.7286 mL |
3.4572 mL |
6.9144 mL |
8.643 mL |
| 10 mM |
0.1729 mL |
0.8643 mL |
1.7286 mL |
3.4572 mL |
4.3215 mL |
| 50 mM |
0.0346 mL |
0.1729 mL |
0.3457 mL |
0.6914 mL |
0.8643 mL |
| 100 mM |
0.0173 mL |
0.0864 mL |
0.1729 mL |
0.3457 mL |
0.4322 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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