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    Yuankanin
    Yuankanin
    Information
    CAS No. 77099-20-8 Price $318 / 5mg
    Catalog No.CFN95128Purity>=98%
    Molecular Weight578.5Type of CompoundFlavonoids
    FormulaC27H30O14Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
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    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $365.7 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
  • University of Wollongong (Australia)
  • Yale University (USA)
  • Johannes Gutenberg University M... (Germany)
  • CSIRO - Agriculture Flagship (Australia)
  • Subang Jaya Medical Centre (Malaysia)
  • University of Minnesota (USA)
  • Cancer Research Initatives Foun... (Malaysia)
  • St. Jude Children Research Hosp... (USA)
  • Nanjing University of Chinese M... (China)
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  • Package
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    Yuankanin

    Yuankanin
    Product Name Yuankanin
    CAS No.: 77099-20-8
    Catalog No.: CFN95128
    Molecular Formula: C27H30O14
    Molecular Weight: 578.5 g/mol
    Purity: >=98%
    Type of Compound: Flavonoids
    Physical Desc.: Powder
    Source: The herbs of Daphne genkwa
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Price: $318 / 5mg
    Inquire / Order: manager@chemfaces.com
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    1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
  • Viruses.2017, 9(10)
  • Molecules.2019, 24(16):E2985
  • Chem Biol Interact.2018, 283:59-74
  • J. of Agricultural Science2015, 1916-9760
  • J Ethnopharmacol.2016, 192:370-381
  • J Pharm Biomed Anal.2018, 151:32-41
  • Sci Rep.2020, 10:4495(2020)
  • Phytomedicine.2021, 2(82):153452
  • Crystals2020, 10(3), 206.
  • Biomolecules.2020, 10(6):925.
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Flavonoids Compound Library
  • Biological Activity
    Description: Reference standards.
    In vitro:
    Phytochemistry. 2008 Jan;69(2):541-5.
    Flavones from Struthiola argentea with anthelmintic activity in vitro.[Pubmed: 17923139 ]
    Parasitic diseases caused by helminthes lead to significant health hazards to animals resulting in enormous economic impact. While a number of anthelmintics are currently available, all are encountering resistance and ones with a mode of action are needed.
    METHODS AND RESULTS:
    We report herein bioassay-guided isolation of three anthelmintic flavones 1-3, including the flavone, 5,6,2',5',6'-pentamethoxy-3',4'-methylenedioxyflavone (3) from the methanol extract of Struthiola argentea (Thymelaeaceae). The structure of 3 was elucidated by analysis of its 1D and 2D NMR and MS data. The two major flavones produced by this plant were also isolated and identified as Yuankanin (4) and amentoflavone (5). A number of flavones related to the compounds isolated from S. argentea were acquired and tested to ascertain structure activity relationships. The isolation, structure, anthelmintic activity and structure activity relationships of the flavones are described.
    CONCLUSIONS:
    Compound 3 exhibited the most potent in vitro activity with 90% inhibition of larval motility at 3.1 microg/mL and compound 15 showed modest in vivo activity.
    Yuankanin Description
    Source: The herbs of Daphne genkwa
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.7286 mL 8.643 mL 17.2861 mL 34.5722 mL 43.2152 mL
    5 mM 0.3457 mL 1.7286 mL 3.4572 mL 6.9144 mL 8.643 mL
    10 mM 0.1729 mL 0.8643 mL 1.7286 mL 3.4572 mL 4.3215 mL
    50 mM 0.0346 mL 0.1729 mL 0.3457 mL 0.6914 mL 0.8643 mL
    100 mM 0.0173 mL 0.0864 mL 0.1729 mL 0.3457 mL 0.4322 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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