ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
3. Inhibitors
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: info@chemfaces.com
Contact Us
Order & Inquiry & Tech Support
Tel: (0086)-27-84237683
Fax: (0086)-27-84254680
E-mail: manager@chemfaces.com
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery time
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $106.7 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Appl Microbiol Biotechnol....2016...Comput Biol Chem.2019, 83:107096Life Sci.2021, 270:119074.BMC Complement Altern Med....2018...Nat Prod Sci.2018, 24(2):109-114Int J Mol Sci.2021, 22(19):10405.Oncol Rep.2021, 46(1):143.J Ethnopharmacol.2020, 269:113752.
Enzyme Microb Technol.2019, 122:64-73Neurochem Int.2020, 133:104629Food Chem.2020, 327:126992.Molecules.2019, 25(1):E103Eur J Pharmacol.2020, 889:173589.Auburn University2015, 1-58bioRxiv2021, 458409.Curr Top Med Chem....2020...
World J Mens Health.2019, 10.5534J Separation Science & Technology...2016...Chinese Medicine2019, 14(1)Korean Journal of Pharmacognosy....2020...Pharmaceutics.2020, 12(9):845.The Journal of Agromedicine and M...2018...Toxins (Basel).2019, 11(10):E575
More...
Our products had been exported to the following research institutions and universities, And still growing.
Calcutta University (India)Research Unit Molecular Epigene... (Germany)Seoul National University of Sc... (Korea)Chiang Mai University (Thailand)
Florida International University (USA)Universite Libre de Bruxelles (Belgium)Imperial College London (United Kingdom)Sri Sai Aditya Institute of Pha... (India)
University of Dicle (Turkey)University of Fribourg (Switzerland)Monash University Sunway Campus (Malaysia)
More...
Picroside III
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
J Cell Physiol.2021, 236(3):1950-1966.J Pharm Biomed Anal.2016, 129:50-59Front Immunol. 2020, 11:62.Med Sci Monit.2019, 25:9499-9508Evid Based Complement Alternat Med.2021, 8855980.Pharm Biol.2016, 54(7):1255-62Cancers (Basel).2021, 13(6):1432.J Ethnopharmacol.2017, 197:157-164Journal of Ginseng Research2021, 25 November Biomed Pharmacother.2021, 144:112300.
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
Iridoids Compound Library |
| Description: |
Picrosides exhibit significant learning and memory deficits, just as Alzheimer's disease(AD) in human. |
| In vitro: |
| J Pharm Biomed Anal. 2013 Jun;80:136-40. | | Pipette tip solid-phase extraction and ultra-performance liquid chromatography/mass spectrometry based rapid analysis of picrosides from Picrorhiza scrophulariiflora.[Pubmed: 23567266] | Pipette tip solid-phase extraction (PT-SPE) is a technique popular in sample preparation of biological fluids and protein hydrolysates.
METHODS AND RESULTS:
In this study, we developed a microtechnic using a pipette tip packed with C18 as sorbent for extraction and purification of bioactive compounds, picroside-I, II and III, in crude herbal extracts from Picrorhiza scrophulariiflora (P. scrophulariiflora). Compared to conventional SPE, PT-SPE is fast, easy to operate, and the tools are very accessible (pipette tip and tube, without expensive SPE set-up). Moreover, it is also cost-effective because significant amount of sorbent and solvents can be saved. The eluate was analyzed by ultra-performance liquid chromatography and tandem mass spectrometry (UPLC-MS/MS). Afterwards, the method was fully validated and the results demonstrated that the PT-SPE-UPLC-MS/MS method is an excellent technique for analysis of the herbal medicine. Finally, this PT-SPE-UPLC-MS/MS strategy was successfully applied to analyze the crude extracts from P. scrophulariiflora samples within 10min (2min for PT-SPE and 8min for UPLC), 3.5mL solvents (including water, 0.3mL for PT-SPE and 3.2mL for UPLC), and 2mg C18 sorbent for each sample.
CONCLUSIONS:
We believe this method to be very practical and, in particular, to be suitable for widespread herbal medicine analysis. |
|
Picroside III Description
| Source: |
The roots of Picrorhiza scrophulariiflora |
| Solvent: |
DMSO, Pyridine, Methanol, Ethanol, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
1.857 mL |
9.2851 mL |
18.5701 mL |
37.1402 mL |
46.4253 mL |
| 5 mM |
0.3714 mL |
1.857 mL |
3.714 mL |
7.428 mL |
9.2851 mL |
| 10 mM |
0.1857 mL |
0.9285 mL |
1.857 mL |
3.714 mL |
4.6425 mL |
| 50 mM |
0.0371 mL |
0.1857 mL |
0.3714 mL |
0.7428 mL |
0.9285 mL |
| 100 mM |
0.0186 mL |
0.0929 mL |
0.1857 mL |
0.3714 mL |
0.4643 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| J Sep Sci. 2011 Aug;34(15):1910-6. | | Counter-current chromatographic method for preparative scale isolation of picrosides from traditional Chinese medicine Picrorhiza scrophulariiflora.[Pubmed: 21721121] | Apocynin, androsin, together with picroside I, picrosideII and Picroside III from crude extracts of Picrorhiza scrophulariiflora were isolated by means of high-speed counter-current chromatography (CCC) combining elution-extrusion (EE) and cycling-elution (CE) approach. The EECCC took full advantages of the liquid nature of the stationary phase for a complete sample recovery and extended the solute hydrophobicity window, while CECCC showed its unique advantage in achieving effective separation of special compounds through preventing stationary phase loss.
METHODS AND RESULTS:
In the present work, the biphasic liquid system composed of n-hexane/ethyl acetate/methanol/water (1:2:1:2, v/v/v/v) was used for separation of apocynin and androsin, ethyl acetate/n-butanol/water/formic acid (4:1:5:0.005, v/v/v/v) for picroside I,picroside II and Picroside III.However, due to the extremely similar K values (K1 /K2 ≈1.2), picroside I and Picroside III were always eluted together by several biphasic solvent systems. In this case, the CECCC exhibited great superiority and baseline separated in the sixth cycle using ethyl acetate/water (1:1, v/v) as biphasic liquid system.
CONCLUSIONS:
Each fraction was analyzed by UPLC-UV and ESI-MS analysis, and identified by comparing with the data of reference substances. Compared with classical elution, the combination of EE and CE approach exhibits strong separation efficiency and great potential to be a high-throughput separation technique in the case of complex samples. |
|
