Info: Read More
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • How to Order
  • Delivery time
  • Science | Nature | Cell | View More
    Natural Products
    Dichotomine B
    Dichotomine B
    Information
    CAS No. 755036-41-0 Price $463 / 5mg
    Catalog No.CFN95193Purity>=98%
    Molecular Weight272.3Type of CompoundAlkaloids
    FormulaC14H12N2O4Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison
    Citing Use of our Products
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $324.1 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
  • National Research Council of Ca... (Canada)
  • Chang Gung University (Taiwan)
  • University of Fribourg (Switzerland)
  • Kamphaengphet Rajabhat University (Thailand)
  • Subang Jaya Medical Centre (Malaysia)
  • Imperial College London (United Kingdom)
  • University of Cincinnati (USA)
  • Research Unit Molecular Epigene... (Germany)
  • Cornell University (USA)
  • National Chung Hsing University (Taiwan)
  • Monash University Sunway Campus (Malaysia)
  • More...
  • Package
    Featured Products
    Gnetol

    Catalog No: CFN92425
    CAS No: 86361-55-9
    Price: $218/5mg
    Voacangine

    Catalog No: CFN92252
    CAS No: 510-22-5
    Price: $463/5mg
    Deapi-platycodin D3

    Catalog No: CFN92269
    CAS No: 67884-05-3
    Price: $238/5mg
    Mulberroside F

    Catalog No: CFN90794
    CAS No: 193483-95-3
    Price: $288/10mg
    Gnetin D

    Catalog No: CFN92423
    CAS No: 84870-53-1
    Price: $468/5mg
    meso-Hannokinol

    Catalog No: CFN90864
    CAS No: N/A
    Price: $368/5mg
    8,8''-Bibaicalein

    Catalog No: CFN95007
    CAS No: 135309-02-3
    Price: $318/5mg

    Dichotomine B

    Dichotomine B
    Product Name Dichotomine B
    CAS No.: 755036-41-0
    Catalog No.: CFN95193
    Molecular Formula: C14H12N2O4
    Molecular Weight: 272.3 g/mol
    Purity: >=98%
    Type of Compound: Alkaloids
    Physical Desc.: Powder
    Source: The herbs of Stellaria dichotoma
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $463 / 5mg
    Inquire / Order: manager@chemfaces.com
    Technical Inquiries: service@chemfaces.com
    Tel: +86-27-84237783
    Fax: +86-27-84254680

    Address:
    1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
  • Eur J Pharmacol.2021, 906:174220.
  • J Ginseng Res.2020, 44(4):611-618.
  • Naunyn Schmiedebergs Arch Pharmacol.2017, 390(10):1073-1083
  • Molecules2020, 25(4):892
  • Malaysian J of Fundamental and Applied Sciences 2018, 14(3):368-373
  • J Sep Sci.2020, 201901140
  • Phytomedicine.2021, 2(82):153452
  • Front Neurosci.2019, 13:1091
  • Integr Cancer Ther.2018, 17(3):832-843
  • Molecules.2020, 25(18),4089.
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Alkaloids Compound Library
  • Biological Activity
    Description: Reference standards.
    Dichotomine B Description
    Source: The herbs of Stellaria dichotoma
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    ChemFaces New Products and Compounds
    Glyasperin C

    Catalog No: CFN95065
    CAS No: 142474-53-1
    Price: $333/5mg
    Safflospermidine A

    Catalog No: CFN95255
    CAS No: N/A
    Price: $413/5mg
    2-Methoxyfuranoguaia-9-ene-8-one

    Catalog No: CFN95220
    CAS No: 88010-62-2
    Price: $318/10mg
    Verbasoside

    Catalog No: CFN95015
    CAS No: 61548-34-3
    Price: $368/5mg
    Daidzein-4'-glucoside

    Catalog No: CFN95142
    CAS No: 58970-69-7
    Price: $368/5mg
    15-Deoxypulic acid

    Catalog No: CFN95262
    CAS No: 95523-05-0
    Price: $368/5mg
    N-trans-p-Coumaroyltyrosine

    Catalog No: CFN95279
    CAS No: 77201-66-2
    Price: $318/10mg
    Lyciumamide B

    Catalog No: CFN95286
    CAS No: 1647111-41-8
    Price: $318/5mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.6724 mL 18.3621 mL 36.7242 mL 73.4484 mL 91.8105 mL
    5 mM 0.7345 mL 3.6724 mL 7.3448 mL 14.6897 mL 18.3621 mL
    10 mM 0.3672 mL 1.8362 mL 3.6724 mL 7.3448 mL 9.1811 mL
    50 mM 0.0734 mL 0.3672 mL 0.7345 mL 1.469 mL 1.8362 mL
    100 mM 0.0367 mL 0.1836 mL 0.3672 mL 0.7345 mL 0.9181 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Nat Prod. 2004 Sep;67(9):1464-9.
    Structures of new beta-carboline-type alkaloids with antiallergic effects from Stellaria dichotoma(1,2).[Pubmed: 21090796 ]
    The aqueous ethanolic extract from the roots of Stellaria dichotoma showed an antiallergic effect on ear passive cutaneous anaphylaxis (PCA) reaction in mice (in vivo) and inhibitory activity on the release of beta-hexosaminidase in RBL-2H3 cells (in vitro).
    METHODS AND RESULTS:
    From the aqueous ethanolic extract, new beta-carboline-type alkaloids, dichotomine A (1), Dichotomine B (2), dichotomine C (3), and dichotomine D (4) and dichotomides I (5) and II (6), were isolated. The structures of the new constituents (1-6) were determined on the basis of chemical and physicochemical evidence, including the application of the modified Mosher's method.
    CONCLUSIONS:
    The effects of the isolated constituents on the release of beta-hexosaminidase in RBL-2H3 cells were examined, and 3 was found to show inhibitory activity (IC(50) = 62 microM). Moreover, 3 also inhibited the releases of antigen-IgE-mediated TNF-alpha and IL-4 (19 and 15 microM, respectively) in RBL-2H3 cells, both of which participate in the late phase of type I allergic reactions.
    Gnetol

    Catalog No: CFN92425
    CAS No: 86361-55-9
    Price: $218/5mg
    Voacangine

    Catalog No: CFN92252
    CAS No: 510-22-5
    Price: $463/5mg
    Deapi-platycodin D3

    Catalog No: CFN92269
    CAS No: 67884-05-3
    Price: $238/5mg
    Mulberroside F

    Catalog No: CFN90794
    CAS No: 193483-95-3
    Price: $288/10mg
    Gnetin D

    Catalog No: CFN92423
    CAS No: 84870-53-1
    Price: $468/5mg
    meso-Hannokinol

    Catalog No: CFN90864
    CAS No: N/A
    Price: $368/5mg
    8,8''-Bibaicalein

    Catalog No: CFN95007
    CAS No: 135309-02-3
    Price: $318/5mg