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Pipernonaline
Pipernonaline
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Pipernonaline
Price: $413 / 5mg
CAS No.: 88660-10-0
Catalog No.: CFN95678
Molecular Formula: C21H27NO3
Molecular Weight: 341.5 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The fruits of Piper nigrum L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $351.1 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Pipernonaline is a piperine derivative with antiprostate cancer activity. Pipernonaline inhibits the proliferation of androgen-dependent/independent LNCaP/PC-3 prostate cells. Pipernonaline activates caspase-3 and promotes procaspase-3/PARP cleavage. Pipernonaline also mediates reactive oxygen species (ROS) production, increased intracellular Ca(2+), and mitochondrial membrane depolarization.
Pipernonaline Description
Source: The fruits of Piper nigrum L.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.9283 mL 14.6413 mL 29.2826 mL 58.5652 mL 73.2064 mL
5 mM 0.5857 mL 2.9283 mL 5.8565 mL 11.713 mL 14.6413 mL
10 mM 0.2928 mL 1.4641 mL 2.9283 mL 5.8565 mL 7.3206 mL
50 mM 0.0586 mL 0.2928 mL 0.5857 mL 1.1713 mL 1.4641 mL
100 mM 0.0293 mL 0.1464 mL 0.2928 mL 0.5857 mL 0.7321 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN95678Pipernonaline88660-10-0341.5C21H27NO3
CFN95691Dehydropipernonaline107584-38-3339.4C21H25NO3
CFN95664Methyl piperate6190-46-1232.2C13H12O4
CFN91121Piperlonguminine5950-12-9273.3C16H19NO3
CFN915084,5-Dihydropiperlonguminine23512-53-0275.4C16H21NO3
CFN95677Pipercide (Retrofractamide B)54794-74-0355.5C22H29NO3
CFN95690Retrofractamide C96386-33-3329.4C20H27NO3
CFN96143Pellitorine18836-52-7223.4C14H25NO
CFN956842,4,12-Octadecatrienoic acid isobutylamide151391-69-4333.6C22H39NO
CFN70461Dodeca 2E,4E,8Z,10E,Z-tetraenoic acid isobutylamide866602-52-0494.8C32H50N2O2
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2,3,5,4'-Tetrahydroxyl diphenyleth...

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CAS No: 82373-94-2
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