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Piptocarphin A
Piptocarphin A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Piptocarphin A
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CAS No.: 76248-63-0
Catalog No.: CFN97688
Molecular Formula: C21H26O9
Molecular Weight: 422.43 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Powder
Source: The herbs of Vernonia volkameriifolia
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Piptocarphin A shows strong cytotoxic activity against mouse lymphoid tumor cell line P388 with the IC(50) value of 0.77 microM.
In vitro:
J Asian Nat Prod Res. 2008 May-Jun;10(5-6):571-5.
Cytotoxic sesquiterpenoids from Vernonia bockiana.[Pubmed: 18470811 ]

METHODS AND RESULTS:
Two new sesquiterpenoids, vernobockolides A (1) and B (2), along with five known ones, piptocarphin C (3), piptocarphin F (4), Piptocarphin A (5), hirsutolide (6), and beta-d-glucopyranosyl taraxinic ester (7), were isolated from the aerial part of Vernonia bockiana. Their structures were determined by spectroscopic analysis, especially 2D NMR.
CONCLUSIONS:
Among them, compounds 2-6 showed strong cytotoxic activities against mouse lymphoid tumor cell line P388 with the IC(50) values of 1.81, 1.32, 0.77, and 0.73 microM, respectively.
Piptocarphin A Description
Source: The herbs of Vernonia volkameriifolia
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3673 mL 11.8363 mL 23.6726 mL 47.3451 mL 59.1814 mL
5 mM 0.4735 mL 2.3673 mL 4.7345 mL 9.469 mL 11.8363 mL
10 mM 0.2367 mL 1.1836 mL 2.3673 mL 4.7345 mL 5.9181 mL
50 mM 0.0473 mL 0.2367 mL 0.4735 mL 0.9469 mL 1.1836 mL
100 mM 0.0237 mL 0.1184 mL 0.2367 mL 0.4735 mL 0.5918 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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Hispidulin

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Nimbolide

Catalog No: CFN91919
CAS No: 25990-37-8
Price: $318/10mg
Crocin I

Catalog No: CFN99927
CAS No: 94238-00-3
Price: $100/20mg
Angeloylgomisin H

Catalog No: CFN90710
CAS No: 66056-22-2
Price: $238/10mg
Pelargonidin chloride

Catalog No: CFN92132
CAS No: 134-04-3
Price: $318/10mg
1-Deoxynojirimycin

Catalog No: CFN99933
CAS No: 19130-96-2
Price: $30/20mg
Ginsenoside Rg5

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Isorhynchophylline

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Echinocystic acid

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CAS No: 510-30-5
Price: $60/20mg
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