ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
3. Inhibitors
Platyphyllenone
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / Inquiry |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Molecules.2017, 22(12)Am J Chin Med.2016, 44(8):1719-1735Front Pharmacol.2022, 13:883475.Int J Mol Sci.2022, 23(23):14545.BMC Plant Biol.2018, 18(1):122JEJU National University2022, 10478.Int Immunopharmacol. 2020, 83:106403.Pharmaceuticals (Basel)....2021...
Nutrients.2018, 10(10)Cell Signal.2022, 99:110433. Evid Based Complement Alternat Me...2017...Int J Mol Sci.2021, 22(21):11836.Molecules.2020, 25(11):2599. Int J Mol Sci.2021, 22(16):8641.Industrial Crops and Products...2022...Preprints2022, 202211.0388.v1.
Separations2021, 8(7),90.Sci Rep. 2018, 1-9Oncol Lett.2020, 20(4):122.Phytomedicine Plus2022, 2(1):100207.Cells.2021, 10(11):2919. Cell Rep.2022, 39(1):110643. J Agric Food Chem.2016, 64(35):6783-90
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Our products had been exported to the following research institutions and universities, And still growing.
University Medical Center Mainz (Germany)University of Liège (Belgium)CSIRO - Agriculture Flagship (Australia)Michigan State University (USA)
Chang Gung University (Taiwan)The Vancouver Prostate Centre (... (Canada)Heidelberg University (Germany)University of Padjajaran (Indonesia)
Institute of Pathophysiology Me... (Austria)Universidad de Antioquia (Colombia)University of Sao Paulo (Brazil)
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Platyphyllenone
Inquire / Order:
manager@chemfaces.com
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service@chemfaces.com
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Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Front Pharmacol.2018, 9:236J Ethnopharmacol.2019, 244:112074J Pharm Biomed Anal.2016, 129:50-59Sci Rep.2019, 9:19059Nutrients.2021, 13(12):4364.Molecules2022, 27(11):3606.Toxicol Appl Pharmacol.2021, 427:115668.J Hematol Oncol.2018, 11(1):112Eur J Pharmacol.2022, 917:174744.Food Funct.2022, 13(14):7638-7649.
Related Screening Libraries
| Description: |
Platyphyllenone has shown promising anti-filarial activity both in vitro and in vivo studies. It can inhibit the biosynthesis of violacein in C. violaceum CV026. |
| Targets: |
Antifection |
| In vitro: |
| Phytomedicine. 2013 Jan 15;20(2):124-32. | | Antifilarial diarylheptanoids from Alnus nepalensis leaves growing in high altitude areas of Uttarakhand, India.[Pubmed: 23219341 ] | Lymphatic filariasis continues to be a major health problem in tropical and subtropical countries. A macrofilaricidal agent capable of eliminating adult filarial parasites is urgently needed. Platyphyllenone (A), alusenone (B), hirustenone (C) and hirsutanonol (D) are important biologically active diarylheptanoids present in Alnus nepalensis.
METHODS AND RESULTS:
In the present study, we report the antifilarial activity in diarylheptanoids isolated from the leaves of Platyphyllenone. nepalensis. Out of four compounds (A-D) tested in vitro one has shown promising anti-filarial activity both in vitro and in vivo studies. |
|
Platyphyllenone Description
| Source: |
The barks of Alnus japonica |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
3.3738 mL |
16.8691 mL |
33.7382 mL |
67.4764 mL |
84.3455 mL |
| 5 mM |
0.6748 mL |
3.3738 mL |
6.7476 mL |
13.4953 mL |
16.8691 mL |
| 10 mM |
0.3374 mL |
1.6869 mL |
3.3738 mL |
6.7476 mL |
8.4345 mL |
| 50 mM |
0.0675 mL |
0.3374 mL |
0.6748 mL |
1.3495 mL |
1.6869 mL |
| 100 mM |
0.0337 mL |
0.1687 mL |
0.3374 mL |
0.6748 mL |
0.8435 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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