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    Natural Products
    Platyphyllenone
    Platyphyllenone
    Information
    CAS No. 56973-65-0 Price
    Catalog No.CFN98955Purity>=98%
    Molecular Weight296.4 Type of CompoundPhenols
    FormulaC19H20O3Physical DescriptionPowder
    Download COA    MSDS    SDF    ManualSimilar structuralComparison (Web)  (SDF)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Platyphyllenone

    Platyphyllenone
    Product Name Platyphyllenone
    CAS No.: 56973-65-0
    Catalog No.: CFN98955
    Molecular Formula: C19H20O3
    Molecular Weight: 296.4 g/mol
    Purity: >=98%
    Type of Compound: Phenols
    Physical Desc.: Powder
    Targets: Antifection
    Source: The barks of Alnus japonica
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Download: COA    MSDS    SDF    Manual
    Similar structural: Comparison (Web)  (SDF)
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  • Front Pharmacol.2018, 9:236
  • J Ethnopharmacol.2019, 244:112074
  • J Pharm Biomed Anal.2016, 129:50-59
  • Sci Rep.2019, 9:19059
  • Nutrients.2021, 13(12):4364.
  • Molecules2022, 27(11):3606.
  • Toxicol Appl Pharmacol.2021, 427:115668.
  • J Hematol Oncol.2018, 11(1):112
  • Eur J Pharmacol.2022, 917:174744.
  • Food Funct.2022, 13(14):7638-7649.
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
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  • Biological Activity
    Description: Platyphyllenone has shown promising anti-filarial activity both in vitro and in vivo studies. It can inhibit the biosynthesis of violacein in C. violaceum CV026.
    Targets: Antifection
    In vitro:
    Phytomedicine. 2013 Jan 15;20(2):124-32.
    Antifilarial diarylheptanoids from Alnus nepalensis leaves growing in high altitude areas of Uttarakhand, India.[Pubmed: 23219341 ]
    Lymphatic filariasis continues to be a major health problem in tropical and subtropical countries. A macrofilaricidal agent capable of eliminating adult filarial parasites is urgently needed. Platyphyllenone (A), alusenone (B), hirustenone (C) and hirsutanonol (D) are important biologically active diarylheptanoids present in Alnus nepalensis.
    METHODS AND RESULTS:
    In the present study, we report the antifilarial activity in diarylheptanoids isolated from the leaves of Platyphyllenone. nepalensis. Out of four compounds (A-D) tested in vitro one has shown promising anti-filarial activity both in vitro and in vivo studies.
    Platyphyllenone Description
    Source: The barks of Alnus japonica
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.3738 mL 16.8691 mL 33.7382 mL 67.4764 mL 84.3455 mL
    5 mM 0.6748 mL 3.3738 mL 6.7476 mL 13.4953 mL 16.8691 mL
    10 mM 0.3374 mL 1.6869 mL 3.3738 mL 6.7476 mL 8.4345 mL
    50 mM 0.0675 mL 0.3374 mL 0.6748 mL 1.3495 mL 1.6869 mL
    100 mM 0.0337 mL 0.1687 mL 0.3374 mL 0.6748 mL 0.8435 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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