Podophyllol | CAS:78339-51-2 | Manufacturer ChemFaces

Podophyllol

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Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
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Podophyllol Description

Source:	The roots of Dysosma versipellis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

J Pharm Sci. 1983 Oct;72(10):1158-61.

Antitumor agents LXII: Synthesis and biological evaluation of podophyllotoxin esters and related derivatives[Pubmed: 6644563 ]

METHODS AND RESULTS:
Synthetic esters of the C-4 hydroxyl group of podophyllotoxin (I) were prepared. In addition, esters were synthesized using the diol system of tetrahydropyranyl Podophyllol (XV), produced by reducing the lactone ring of tetrahydropyranyl podophyllotoxin with lithium aluminum hydride. Six compounds, the acrylate (IV), 3,3-dimethyl acrylate (V), phenoxyacetate (IX), and ethyl adipate (XI) of I as well as Podophyllol (XIV) and tetrahydropyranyl Podophyllol dimesylate (XVIII), showed significant activity when tested using the P-388 lymphocytic leukemia screen at 3 mg/kg/day.
CONCLUSIONS:
None of the esters showed higher activity than that shown by the parent molecule I when tested at the same dosage level.

Product Name	Podophyllol
Price:
CAS No.:	78339-51-2
Catalog No.:	CFN93333
Molecular Formula:	C₂₂H₂₆O₈
Molecular Weight:	418.44 g/mol
Purity:	>=98%
Type of Compound:	Lignans
Physical Desc.:	Powder
Source:	The roots of Dysosma versipellis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Lignans Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.3898 mL	11.9491 mL	23.8983 mL	47.7966 mL	59.7457 mL
5 mM	0.478 mL	2.3898 mL	4.7797 mL	9.5593 mL	11.9491 mL
10 mM	0.239 mL	1.1949 mL	2.3898 mL	4.7797 mL	5.9746 mL
50 mM	0.0478 mL	0.239 mL	0.478 mL	0.9559 mL	1.1949 mL
100 mM	0.0239 mL	0.1195 mL	0.239 mL	0.478 mL	0.5975 mL

CFN95336	Peiioside B	1610618-91-1	594.6	C₂₅H₃₈O₁₆
CFN92317	Carbamic acid	84640-31-3	224.2	C₁₀H₁₂N₂O₄
CFN99229	3-Deoxysappanone B	113122-54-6	286.3	C₁₆H₁₄O₅
CFN99711	Sipeimine	61825-98-7	429.64	C₂₇H₄₃NO₃