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    Natural Products
    Rhein-8-glucoside calcium salt
    Information
    CAS No. 113443-70-2 Price
    Catalog No.CFN99592Purity>=98%
    Molecular Weight484.43Type of CompoundAnthraquinones
    FormulaC21H16O11.CaPhysical DescriptionYellow powder
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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    Rhein-8-glucoside calcium salt

    Rhein-8-glucoside calcium salt
    Product Name Rhein-8-glucoside calcium salt
    CAS No.: 113443-70-2
    Catalog No.: CFN99592
    Molecular Formula: C21H16O11.Ca
    Molecular Weight: 484.43 g/mol
    Purity: >=98%
    Type of Compound: Anthraquinones
    Physical Desc.: Yellow powder
    Targets: hPTP1B
    Source: The roots of Rheum palmatum L.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Price:
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Inhibitors Compound Library
  • Anthraquinones Compound Library
  • Biological Activity
    Description: Rhein-8-O-beta-D-glucopyranoside(Rhein-8-glucoside calcium salt) shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro.
    Targets: hPTP1B
    In vitro:
    J Asian Nat Prod Res. 2006 Apr-May;8(3):281-6.
    PTP1B inhibitors from Saussrurea lappa.[Pubmed: 16864436 ]

    METHODS AND RESULTS:
    A new lignan glycoside, named 1,5-dihydroxypinoresinol-4'-O-beta-d-glucopyranoside (1), has been isolated from the EtOH extract of the roots of Saussurea lappa, together with twenty known compounds: (+)-1-hydroxypinoresinol-1-O-beta-D-glucopyranoside (2), fraxiresinol-4'-O-beta-D-glucopyranoside (3), (-)-olivil-4''-O-beta-D-glucopyranoside (4), 4-allyl-2,6-dimethoxybenzene-1-O-beta-D-glucopyranoside, syringin, costunolide-15-O-beta-D-glucopyranoside, chlorogenic acid, aloe-emodin-8-O-beta-D-glucopyranoside (5), rhein-8-O-beta-D-glucopyranoside (Rhein-8-glucoside calcium salt),6), chrysophanol (7), emodin, dehydrocostus lactone, costunolide, beta-costic acid, reynosin, arbusculin A, alpha-cyclocostunolide, beta-cyclocostunolide, santamarine and magnolialide.
    CONCLUSIONS:
    Three anthraquinones (5-7) showed moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro.
    Rhein-8-glucoside calcium salt Description
    Source: The roots of Rheum palmatum L.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.0643 mL 10.3214 mL 20.6428 mL 41.2856 mL 51.607 mL
    5 mM 0.4129 mL 2.0643 mL 4.1286 mL 8.2571 mL 10.3214 mL
    10 mM 0.2064 mL 1.0321 mL 2.0643 mL 4.1286 mL 5.1607 mL
    50 mM 0.0413 mL 0.2064 mL 0.4129 mL 0.8257 mL 1.0321 mL
    100 mM 0.0206 mL 0.1032 mL 0.2064 mL 0.4129 mL 0.5161 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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