Rosarin | CAS:84954-93-8 | Manufacturer ChemFaces

Rosarin

ChemFaces products have been cited in many studies from excellent and top scientific journals

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $141.7 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Rosarin is a natural product from Rhodiola rosea L.

In vivo:

Evid Based Complement Alternat Med. 2013;2013:514049.

Anti-Inflammatory and Neuroprotective Effects of Constituents Isolated from Rhodiola rosea.[Pubmed: 23690847]

METHODS AND RESULTS:
To determine the biological activity of Rhodiola rosea, the protein expression of iNOS and proinflammatory cytokines was measured after the activation of murine microglial BV2 cells by LPS under the exposure of constituents of Rhodiola rosea: crude extract, rosin, Rosarin, and salidroside (each 1-50 μ g/mL). The LPS-induced expression of iNOS and cytokines in BV2 cells was suppressed by the constituents of Rhodiola rosea in a concentration-dependent manner. Also the expression of the proinflammatory factors iNOS, IL-1 β , and TNF- α in the kidney and prefrontal cortex of brain in mice was suppressed by the oral administration of Rhodiola rosea crude extract (500 mg/kg). To determine the neuroprotective effect of constituents of Rhodiola rosea, neuronal cells were activated by L-glutamate, and neurotoxicity was analyzed. The L-glutamate-induced neurotoxicity was suppressed by the treatment with rosin but not by Rosarin. The level of phosphorylated MAPK, pJNK, and pp38 was increased by L-glutamate treatment but decreased by the treatment with rosin and salidroside.
CONCLUSIONS:
These results indicate that Rhodiola rosea may have therapeutic potential for the treatment of inflammation and neurodegenerative disease.

Rosarin Description

Source:	The herbs of Rhodiola rosea L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Rosarin
Price:	$238 / 10mg
CAS No.:	84954-93-8
Catalog No.:	CFN99178
Molecular Formula:	C₂₀H₂₈O₁₀
Molecular Weight:	428.43 g/mol
Purity:	>=98%
Type of Compound:	Phenylpropanoids
Physical Desc.:	Powder
Source:	The herbs of Rhodiola rosea L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Phenylpropanoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.3341 mL	11.6705 mL	23.341 mL	46.6821 mL	58.3526 mL
5 mM	0.4668 mL	2.3341 mL	4.6682 mL	9.3364 mL	11.6705 mL
10 mM	0.2334 mL	1.1671 mL	2.3341 mL	4.6682 mL	5.8353 mL
50 mM	0.0467 mL	0.2334 mL	0.4668 mL	0.9336 mL	1.1671 mL
100 mM	0.0233 mL	0.1167 mL	0.2334 mL	0.4668 mL	0.5835 mL

CFN98886	Coniferin	531-29-3	342.3	C₁₆H₂₂O₈
CFN95546	(Z)-Ferulic acid 4-O-beta-D-glucoside	94942-20-8	356.3	C₁₆H₂₀O₉
CFN95629	cis-2-Hydroxy 4-methoxycinnamic acid 2-glucoside	150892-86-7	356.3	C₁₆H₂₀O₉
CFN95631	2-Glucosyloxy-4-methoxycinnamic acid (Z-GMCA)	31564-49-5	356.3	C₁₆H₂₀O₉
CFN93040	Sargentol	623928-18-7	388.36	C₁₇H₂₄O₁₀
CFN99282	Syringin	118-34-3	372.4	C₁₇H₂₄O₉
CFN97483	Syringin pentaacetate	92233-55-1	582.6	C₂₇H₃₄O₁₄
CFN95040	Cordifolioside A	155179-20-7	504.5	C₂₂H₃₂O₁₃
CFN95108	Tangshenoside I	117278-74-7	678.6	C₂₉H₄₂O₁₈
CFN99648	Sinapaldehyde glucoside	154461-65-1	370.4	C₁₇H₂₂O₉