ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
3. Inhibitors
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / Inquiry |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Acta Chromatographica2016, 29(3)Universidade Estadual Paulista...2017...BMC Complement Altern Med....2018...Korean Journal of Medicinal Crop ...2018...Front Pharmacol.2019, 10:1226Front Neurosci.2019, 13:1091J Ethnopharmacol.2019, 228:132-141Molecules.2019, 24(16):E2985
Molecules.2019, 24(6):E1155Food Chem.2019, 276:768-775Phytomedicine.2019, 59:152785Int Immunopharmacol.2019, 71:361-371Oxid Med Cell Longev2020, 12Appl. Sci.2020, 10(8),2804Front Immunol. 2020, 11:62.Pharmaceutics.2020, 12(9):845.
Biomed Pharmacother.2020, 131:110673.BMC Complement Med Ther. ...2020...Analytical sci. & Tech...2020...Food Addit Contam Part A Chem Ana...2020...Horticulture Research2020, 7:111. Chem. of Vegetable Raw Materials...2020...Chung Shan Medical University...2020...
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Our products had been exported to the following research institutions and universities, And still growing.
Aveiro University (Portugal)Agricultural Research Organizat... (Israel)Istanbul University (Turkey)Max Rubner-Institut (MRI) (Germany)
Sapienza University of Rome (Italy)The Ohio State University (USA)University of Medicine and Phar... (Romania)Instituto de Investigaciones Ag... (Chile)
Seoul National University (Korea)Utah State University (USA)Uniwersytet JagielloĊski w Kra... (Poland)
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Thamnosmonin
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manager@chemfaces.com
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service@chemfaces.com
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+86-27-84254680
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1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Front Pharmacol.2017, 8:205Phytother Res.2016, 30(12):2020-2026Biol Pharm Bull.2017, 40(6):797-806Phytomedicine.2019, 55:229-237Molecules.2020, 25(9):2081.Int Immunopharmacol.2019, 71:361-371Chem Biol Interact.2020, 328:109200.American Association for Anatomy2020, doi: 10.1002.J Insect Sci.2020, 20(5):18. Korean Journal of Pharmacognosy2019, 50(4):285-290
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
Coumarins Compound Library |
| Description: |
Thamnosmonin is a natural product from Citrus sinensis. |
| In vitro: |
| Phytother Res. 2007 Apr;21(4):386-90. | | Modulation of P-glycoprotein activity by acridones and coumarins from Citrus sinensis.[Pubmed: 17236173 ] |
METHODS AND RESULTS:
Bioguided fractionation of the roots of Citrus sinensis (Rutaceae) led to the isolation and identification of five coumarins, namely, clausarin, suberosin, poncitrin, xanthyletin and Thamnosmonin, seven acridones, namely, acrimarine B, 2-methoxycitpressine I, citpressine I, buntanine, acrimarine E, honyumine and acrimarine C, and one terpenoid, namely, limonin.
CONCLUSIONS:
Among these compounds, clausarin, 2-methoxycitpressine I and acrimarine E inhibited P-glycoprotein-mediated drug efflux in K562/R7 human leukemic cells over-expressing P-glycoprotein. |
|
Thamnosmonin Description
| Source: |
The roots of Citrus sinensis. |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
3.6195 mL |
18.0976 mL |
36.1952 mL |
72.3903 mL |
90.4879 mL |
| 5 mM |
0.7239 mL |
3.6195 mL |
7.239 mL |
14.4781 mL |
18.0976 mL |
| 10 mM |
0.362 mL |
1.8098 mL |
3.6195 mL |
7.239 mL |
9.0488 mL |
| 50 mM |
0.0724 mL |
0.362 mL |
0.7239 mL |
1.4478 mL |
1.8098 mL |
| 100 mM |
0.0362 mL |
0.181 mL |
0.362 mL |
0.7239 mL |
0.9049 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| Zhong Yao Cai. 2013 May;36(5):744-6. | | Study on the chemical constituents from ethyl acetate extract of Micromelum falcatum.[Pubmed: 24218965] | To study the chemical constituents from ethyl acetate extract of Micromelum falcatum.
METHODS AND RESULTS:
The constituents were separated and purified by silica gel, Sephadex LH-20 and HPLC. Their structures were elucidated by spectral analysis (NMR, MS).
Ten compounds were isolated and identified as micropubescin (1), phebalosin (2), scopoletin (3), citrubuntin (4), Thamnosmonin (5), hopeyhopin (6), arnottinin (7), casegravol (8), 2-methoxy-5-hydroxy cinnamate (9), threo-syringoylglycerol (10).
CONCLUSIONS:
Compounds 1 - 10 are obtained from this plant for the first time. |
|
