cis-Miyabenol C | CAS:168037-22-7 | Manufacturer ChemFaces

cis-Miyabenol C

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Description:

cis-Miyabenol C exhibits antioxidative activities and shows strong hyaluronidase inhibitory effects. cis-Miyabenol C also has ecdysteroid antagonist activity.

In vitro:

J Sci Food Agric. 2014 Mar 30;94(5):951-4.

Bioactive stilbenes from Vitis vinifera grapevine shoots extracts.[Pubmed: 23929536]

METHODS AND RESULTS:
A new resveratrol oligomer, (Z)-cis-Miyabenol C (3), was isolated from Vitis vinifera grapevine shoots together with two newly reported oligostilbenes from Vitis vinifera shoots, vitisinol C (1) and (E)-cis-Miyabenol C (2), and six known compounds: piceatannol, resveratrol, (E)-ε-viniferin (trans-ε-viniferin), ω-viniferin, vitisinol C and (E)-miyabenol C. The structures of these resveratrol derivatives were established on the basis of detailed spectroscopic analysis including nuclear magnetic resonance experiments. All the newly reported compounds were tested for their anti-aggregative activity against amyloid-β fibril formation.
CONCLUSIONS:
Vitisinol C was found to exert a significant activity against amyloid-β aggregation.

Phytochemistry. 2001 Jun;57(3):393-400.

Identification and ecdysteroid antagonist activity of three oligostilbenes from the seeds of Carex pendula (Cyperaceae).[Pubmed: 11393519]

Methanolic extracts of seeds of several (Carex species were found to antagonise the action of 20-hydroxyecdysone in the Drosophila melanogaster microplate-based B(II) cell bioassay.
METHODS AND RESULTS:
Bioassay-guided HPLC analysis of seeds of Carex pendula (drooping sedge) provided one previously unknown tetrastilbene (cis-miyabenol A) and two known oligostilbenes (kobophenol B and cis-Miyabenol C) as the biologically active compounds (EC50 values were 31, 37 and 19 microM, respectively, vs. 5 x 10(-8) M 20-hydroxyecdysone). The structures and relative stereochemistries of these compounds were deduced by comprehensive ID- and 2D-NMR experiments. These compounds are isolated from Carex pendula for the first time.
CONCLUSIONS:
In vitro experiments with dipteran and lepidopteran ecdysteroid receptor proteins demonstrate that the oligostilbenes are able to compete with radiolabelled ecdysteroid ([3H]ponasterone A) for occupancy of the ligand binding site. IC50/Ki values are similar to the EC50 values obtained in the B(II) bioassay.

cis-Miyabenol C Description

Source:	The herbs of Vitis vinifera
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	cis-Miyabenol C
Price:
CAS No.:	168037-22-7
Catalog No.:	CFN92387
Molecular Formula:	C₄₂H₃₂O₉
Molecular Weight:	680.7 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The herbs of Vitis vinifera
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antioxidants Compound Library Ecdysteroid antagonists Compound Library Antihyaluronidase Compound Library Phenols Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.4691 mL	7.3454 mL	14.6908 mL	29.3815 mL	36.7269 mL
5 mM	0.2938 mL	1.4691 mL	2.9382 mL	5.8763 mL	7.3454 mL
10 mM	0.1469 mL	0.7345 mL	1.4691 mL	2.9382 mL	3.6727 mL
50 mM	0.0294 mL	0.1469 mL	0.2938 mL	0.5876 mL	0.7345 mL
100 mM	0.0147 mL	0.0735 mL	0.1469 mL	0.2938 mL	0.3673 mL

CFN95042	Carasinol B	777857-86-0	925.0	C₅₆H₄₄O₁₃
CFN93787	(-)-Ampelopsin H	N/A	907.0	C₅₆H₄₂O₁₂
CFN97068	alpha-Viniferin	62218-13-7	678.7	C₄₂H₃₀O₉
CFN98469	Caraphenol A	354553-35-8	676.7	C₄₂H₂₈O₉
CFN97082	Viniferol D	625096-18-6	680.7	C₄₂H₃₂O₉
CFN96132	Mulberrofuran C	77996-04-4	580.6	C₃₄H₂₈O₉
CFN92788	Mulberrofuran G	87085-00-5	562.6	C₃₄H₂₆O₈
CFN96253	Mulberrofuran G pentaacetate	99217-75-1	772.8	C₄₄H₃₆O₁₃
CFN96881	Mulberrofuran K	94617-36-4	628.67	C₃₉H₃₂O₈
CFN92853	Gnetumontanin B	809237-87-4	713.0	C₄₂H₃₂O₁₁