ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
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3. Inhibitors
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $301.0 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
Acta Agriculturae Scandinavica...2015...J Pharm Biomed Anal2016, 118:183-194HortTechnology2016, 26(6):816-819Acta Chromatographica2016, 29(3)J of the Korean Society of Food S...2016...Tea Res. Ins. Of China2017, 1-12J Nat Med.2017, 71(4):745-756Oncotarget.2017, 9(3):4161-4172
Nutrients.2018, 10(10)Nutrients.2018, 10(12):E1998Korean J of Medicinal Crop Scienc...2018...Molecules.2018, 23(9):E2121Nat Prod Sci.2018, 24(3):206Exp Ther Med.2019, 18(6):4388-4396J Med Food.2019, 22(10):1067-1077J Funct Foods2019, 54:449-456
J of Applied Pharmaceutical Scien...2020...Saudi Pharm J2020, 10.1016Plant Cell, Tissue and Organ Cult...2020...Anesth Pain Med (Seoul)....2020...Int J Mol Sci.2020, 21(9):3392. Horticulturae2020, 6(4),76.Antioxidants (Basel).2020, 9(6):544.
More...
Our products had been exported to the following research institutions and universities, And still growing.
University of East Anglia (United Kingdom)Massachusetts General Hospital (USA)The Australian National University (Australia)Research Unit Molecular Epigene... (Germany)
University of Parma (Italy)Universidade Federal de Goias (... (Brazil)Universita' Degli Studi Di Cagl... (Italy)Universit?t Basel (Switzerland)
Northeast Normal University Cha... (China)Monash University Malaysia (Malaysia)Max-Planck-Insitut (Germany)
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cis-Mulberroside A
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manager@chemfaces.com
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service@chemfaces.com
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+86-27-84254680
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J Chromatogr B Analyt Technol Biomed Life Sci.2020, 1149:122123.J Ethnopharmacol.2018, 210:88-94Psychopharmacology (Berl).2020, 10.1007Biomed Chromatogr.2016, 30(10):1573-81Mol Microbiol.2019, 112(1):317-332Appl. Sci.2021, 11(1),14.J Chromatogr Sci.2015, 53(5):824-9Food Research2021, 5(1):65-71Phytomedicine.2018, 38:12-23Evid Based Complement Alternat Med.2017, 2017:1583185
Related Screening Libraries
| Description: |
cis-Mulberroside A shows high analgesic and anti-inflammatory activities, it can protect mice against ethanol-induced hepatic damage. |
| Targets: |
TNF-α | NO | NOS |
| In vivo: |
| Environ. Toxicol. Pharmacol., 2008,26(3):325-30. | | Protective function of cis-mulberroside A and oxyresveratrol from Ramulus mori against ethanol-induced hepatic damage.[Pubmed: 21791383 ] | The aim of the study was to investigate the protective effects of oxyresveratrol and cis-Mulberroside A isolated from Ramulus mori on the liver of mice intoxicated with ethanol.
METHODS AND RESULTS:
Animals were pretreated with different doses (30 and 60mg/kg of body weight) of oxyresveratrol and cis-Mulberroside A prior to the ethanol (9g/kg of body weight) orally for 7 days. Ethanol treatment induced the decrease of reduced glutathione level and antioxidant enzymes activities, the elevation of the lipid peroxidation and cytochrome P450 2E1 activity accompanied with the increase of iron concentration and mitochondrial permeability transition. Pretreatment with oxyresveratrol and cis-Mulberroside A restored the changes in the above parameters up to the basal level. The protective effects of the two active compounds were further supported by attenuation of the degree of tissue damage and the regulation of the expression of TNF-α.
CONCLUSIONS:
It could be concluded that oxyresveratrol and cis-Mulberroside A from R. mori could protect mice against ethanol-induced hepatic damage. |
|
cis-Mulberroside A Description
| Source: |
The root barks of Morus alba L. |
| Solvent: |
DMSO, Pyridine, Methanol, Ethanol, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
1.759 mL |
8.7948 mL |
17.5895 mL |
35.1791 mL |
43.9738 mL |
| 5 mM |
0.3518 mL |
1.759 mL |
3.5179 mL |
7.0358 mL |
8.7948 mL |
| 10 mM |
0.1759 mL |
0.8795 mL |
1.759 mL |
3.5179 mL |
4.3974 mL |
| 50 mM |
0.0352 mL |
0.1759 mL |
0.3518 mL |
0.7036 mL |
0.8795 mL |
| 100 mM |
0.0176 mL |
0.0879 mL |
0.1759 mL |
0.3518 mL |
0.4397 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Animal Research: |
| Fitoterapia, 2009, 81(3):214-8. | | Anti-inflammatory and analgesic properties of cis-mulberroside A from Ramulus mori.[Pubmed: 19755140 ] | This study examined the analgesic and anti-inflammatory actions of cis-Mulberroside A isolated from Ramulus mori in several models of inflammatory pain in mice.
METHODS AND RESULTS:
cis-Mulberroside A (25 and 50mg/kg) given by p.o. route 30 min before challenge produced a dose-dependent inhibition of the acetic acid-induced pain and Evans blue leakage in mice. In addition, this compound exhibited significant systemic anti-inflammatory activity in carrageenan-induced mouse paw edema in a concentration-related manner (33.1-68.5% inhibition), and similar results were achieved in formalin test. Suppressive effects of cis-Mulberroside A on the production of NO and expression of inducible nitric oxide synthase (iNOS) in lipopolysaccharide (LPS)-stimulated macrophages were also assessed. Collectively, cis-Mulberroside A showed high analgesic and anti-inflammatory activities.
CONCLUSIONS:
The above results will be the supporting evidence for the potential anti-rheumatoid activity of R.mori in Chinese traditional medicine. |
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