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    Natural Products
    Hederagenin 3-O-(2-O-acetyl-alpha-L-arabinopyranoside)
    Hederagenin 3-O-(2-O-acetyl-alpha-L-arabinopyranoside)
    Information
    CAS No. 87562-05-8 Price $318 / 10mg
    Catalog No.CFN95355Purity>=98%
    Molecular Weight646.9Type of CompoundTriterpenoids
    FormulaC37H58O9Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $251.2 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Hederagenin 3-O-(2-O-acetyl-alpha-L-arabinopyranoside)

    Hederagenin 3-O-(2-O-acetyl-alpha-L-arabinopyranoside)
    Product Name Hederagenin 3-O-(2-O-acetyl-alpha-L-arabinopyranoside)
    CAS No.: 87562-05-8
    Catalog No.: CFN95355
    Molecular Formula: C37H58O9
    Molecular Weight: 646.9 g/mol
    Purity: >=98%
    Type of Compound: Triterpenoids
    Physical Desc.: Powder
    Source: The herbs of Caulophyllum robustum
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Price: $318 / 10mg
    Inquire / Order: manager@chemfaces.com
    Technical Inquiries: service@chemfaces.com
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Triterpenoids Compound Library
  • Biological Activity
    Description: Hederagenin 3-O-(2-O-acetyl-α-L-arabinopyranoside) significantly increased alkaline phosphatase (ALP) activity and the level of protein expression of bone sialoprotein (BSP) and osteocalcin (OC) .
    In vitro:
    Biosci Biotechnol Biochem . 2011;75(1):13-19.
    Effects of the dichloromethane fraction of Dipsaci Radix on the osteoblastic differentiation of human alveolar bone marrow-derived mesenchymal stem cells[Pubmed: 21228489]
    Dipsaci Radix is the dried root of Dipsacus asper Wall. It has been used in Korean herbal medicine to treat bone fractures. In this study, we examined the effect of the dichloromethane fraction of Dipsaci Radix (DR(DM)) on the osteoblastic differentiation of human alveolar bone marrow-derived MSCs (ABM-MSCs). The ABM-MSCs were isolated from healthy subjects and cultured in vitro, followed by phenotypic characterization. They showed a fibroblast-like morphology and expressed CD29, CD44, CD73, and CD105, but not CD34. Calcified nodules were generated in response to both dexamethasone (DEX) and DR(DM). There was a significant increase in the alkaline phosphatase (ALP) activity and protein expression of bone sialoprotein (BSP) and osteocalcin (OC) in response to DEX and DR(DM) as compared to control. These results provide evidence for the osteogenic potential of cultured ABM-MSCs in response to DR(DM). Also, an active single compound was additionally isolated from DR(DM). The single compound (hederagenin 3-O-(2-O-acetyl)-α-L-arabinopyranoside) also significantly increased ALP activity and the level of protein expression of BSP and OC. These results highlight the possible clinical applications of DR(DM) and hederagenin 3-O-(2-O-acetyl)-α-L-arabinopyranoside in bone regeneration.
    Hederagenin 3-O-(2-O-acetyl-alpha-L-arabinopyranoside) Description
    Source: The herbs of Caulophyllum robustum
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.5458 mL 7.7292 mL 15.4583 mL 30.9167 mL 38.6458 mL
    5 mM 0.3092 mL 1.5458 mL 3.0917 mL 6.1833 mL 7.7292 mL
    10 mM 0.1546 mL 0.7729 mL 1.5458 mL 3.0917 mL 3.8646 mL
    50 mM 0.0309 mL 0.1546 mL 0.3092 mL 0.6183 mL 0.7729 mL
    100 mM 0.0155 mL 0.0773 mL 0.1546 mL 0.3092 mL 0.3865 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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