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Natural Products
Catalog No. Information
CFN70197 Cedrol

Cedrol shows antifungal activity against the fungus Botrytis cinerea , it has the potential of becoming a new hair growth promoter. Cedrol has sedative effects, it induces autophagy and apoptotic cell death in A549 non-small cell lung carcinoma cells through the P13K/Akt signaling pathway, the loss of mitochondrial transmembrane potential and the generation of ROS. Cedrol is a potent competitive inhibitor of CYP2B6-mediated bupropion hydroxylase with the inhibition constant (Ki) value of 0.9, μM, it also markedly inhibited CYP3A4-mediated midazolam hydroxylation with a Ki value of 3.4 μM.
CFN97237 Cedrusin

Cedrusin shows a cytotoxic effect on A375 and HeLa cells.
CFN99198 Celastrol

Celastrol is a potent proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with IC50 of 2.5 μM. Celastrol is also a novel HSP90 inhibitor, it has anti-proliferative, anti-inflammatory, anti-tumor , antiangiogenesis, and antioxidant activities. Celastrol inhibits Plasmodium falciparum enoyl-acyl carrier protein reductase and inhibits VEGF receptors expression.
CFN60123 Celecoxib

CFN91669 Celosin H

Celosin H is a novel hepatoprotective triterpenoid saponin isolated from the methanol extract of Celosiae Semen.
CFN91061 Celosin I

Celosin H, celosin I, and celosin J could be used as chemical markers for the quality control of C. argentea seeds. Celosin I exhibited significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in mice.
CFN90433 Centaureidin

Centaureidin augments IFN-gamma promoter activity by approximately four-fold. Centaureidin shows potential vasorelaxant activity. It inhibits dendrite outgrowth from melanocytes by activating Rho, resulting in the inhibition of melanosome transfer from melanocytes to keratinocytes.
CFN98383 Centrolobol

(-)-Centrolobol has antifibrotic activity, it can significantly inhibit the proliferation of HSC-T6 cells in a dose-dependent manner. Centrolobol exhibits strong cytotoxic activity against KB cell line.
CFN93317 Cephaeline

Cephaeline was highly active against protected primary CLL cells (relative IC50's 35 nM ) and acted by repressing HIF-1α and disturbing intracellular redox homeostasis.
CFN70419 Cephaeline dihydrobromide

Reference standards.