Hot Products
Catalog No. | Information |
CFN90407 | Dehydrocavidine Dehydrocorydaline has antitumor activity, it inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP. Dehydrocorydaline inhibits the elevation of mitochondrial membrane potential and induces ATP depletion in LPS-stimulated macrophages but neither affects basal mitochondrial membrane potential nor ATP content in non-stimulated macrophages. |
CFN90330 | Dehydrocorydalin Dehydrocorydalin has anti-inflammatory,antinociceptive,antiplatelet,and anti-tumor effects and can protect the cardiovascular system. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimerization of MyoD and E proteins, thus resulting in MyoD activation and myoblast differentiation. Dehydrocorydaline inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP. |
CFN90604 | Dehydrocorydaline nitrate Dehydrocorydaline has anti-inflammatory activity, it has antinociceptive effects in mouse models of inflammatory pain, the effects involve the opioid receptor and inflammatory cytokines. Dehydrocorydaline can inhibit elevated mitochondrial membrane potential in lipopolysaccharide-stimulated macrophages.Dehydrocorydaline not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect of Corydalis Tuber on allergic reactions may be partially attributed to dehydrocorydaline. |
CFN98720 | Dehydrocostus lactone Dehydrocostus lactone (DHE), a natural sesquiterpene lactone, inhibits IKKβ, Wnt/β-catenin activity, IκBα phosphorylation and degradation, coactivators p300 recruitments and p50/p65 NF-κB nuclear translocation, and their DNA binding activity on COX-2 promoter. DHE has anti-inflammatory, antioxidant, anti-ulcer, immunomodulatory and anti-tumor properties, it can against osteoblast damage induced by AMA and cervical cancer. DHE exhibits strong larvicidal activity against A. albopictus with LC(50) values of 2.34 ug/ml. |
CFN97116 | Dehydrocrenatidine Dehydrocrenatidine is a JAK-specific inhibitor, can inhibit JAK-STAT3-dependent DU145 and MDA-MB-468 cell survival and induce cell apoptosis. |
CFN98312 | Dehydrocrenatine Reference standards. |
CFN96567 | Dehydrodiconiferyl alcohol Dehydrodiconiferyl alcohol shows anti-adipogenic and anti-lipogenic effects in 3T3-L1 cells and primary mouse embryonic fibroblasts. Dehydrodiconiferyl alcohol can modulate the differentiation of Th17 and Th1 cells and suppress experimental autoimmune encephalomyelitis, it may be a potential candidate as an agent for the control of Th17 and Th1-mediated inflammatory diseases. (+)-(2S,3R)-Dehydrodiconiferyl alcohol is an antioxidant, it has an inhibitory effect on VCAM-1 expression via JNK pathway in endothelial cells and therefore may serve as a novel pharmacological agent to improve endothelial dysfunction. |
CFN89430 | Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside is a natural product from Ligusticopsis wallichiana (DC) Pimenov & Kljuykov. |
CFN99750 | Dehydrodiisoeugenol Dehydrodiisoeugenol has anti-inflammatory activity, it inhibited the expression of the COX-2, proteolysis of inhibitor κB-α and transcriptional activity of NF-κB. Dehydrodiisoeugenol can cross the blood-brain barrier rapidly, it may be developed into an effective anxiogenic agent. |
CFN92740 | Dehydroeburicoic acid Dehydroeburicoic acid induces necrotic cell death that involves Ca(2+) overload, mitochondrial dysfunction, and calpain activation in human glioblastomas. Dehydroeburicoic acid and Eburicoic acid have antioxidant and anti-inflammatory activities by the decrease of inflammatory cytokines and an increase of antioxidant enzyme activity, can protect the liver from CCl4-induced hepatic damage. |