Hot Products
Catalog No. | Information |
CFN92363 | Didymin Didymin is a citrus-derived natural compound that kills p53 wild-type as well as drug-resistant p53-mutant neuroblastoma cells in culture, it induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma. Didymin possesses antioxidant, anti-inflammation and anti-cancer properties. |
CFN91592 | Dieckol Dieckol has been exhibited a broad spectrum of therapeutic functions including anti-bacterial, anti-cancer, anti-oxidant, anti-aging, anti-diabetic, neuroprotective, and other medicinal applications. Dieckol plays an important role in apoptosis induction via inhibiting the PI3K, AKT, mTOR and FAK signaling molecules. Dieckol remarkably inhibited the lipid accumulation in high fat diet induced animal models,decreased the size of LDs and modulated the contribution of LDs to less toxic ones by decreasing PLIN2 expression and thus attenuated muscle atrophy and strength, which were induced by HF. |
CFN92536 | Digiferruginol Digiferruginol has cytotoxic activity. Digiferruginol and hederagenin show weak effect on porcine respiratory and reproductive syndrome virus (PRRSV) with an IC50 value of 80.5 ± 16.9 uM(SI = 19.9) and 43.2 ± 7.4 uM (SI = 13.1), respectively. |
CFN92109 | Digitolutein Digitolutein has inhibition on the growth of Plasmodium falciparum in vitro. |
CFN92831 | Digitonin Digitonin can increase cell permeability by binding to cholesterol molecules and reduce tumor growth. Digitonin solubilizes mitochondrial membrane, breaks the integrity of the respiratory chain and releases two mobile redox-active components: coenzyme Q (CoQ) and cytochrome c (cyt c). |
CFN98536 | Digoxin Digoxin is a classical Na,K-ATPase inhibitor, with selectivity for the α2β3 isoform over the common α1β1 isoform, used in the treatment of atrial fibrillation and heart failure. Digoxin and other cardiac glycosides can inhibit hypoxia-inducible factor 1 (HIF-1)α synthesis and block tumor growth. |
CFN96580 | Dihydroactinidiolide Dihydroactinidiolide, a high light-induced β-carotene derivative that can regulate gene expression and photoacclimation in Arabidopsis. Dihydroactinidiolide has shown to be a potent phytotoxin at low concentration, it may have interesting potential anticancer activity. |
CFN93295 | Dihydroartemisinic acid Dihydroartemisinic acid is a precursor to the antimalarial agent artemisinin. |
CFN99507 | Dihydroartemisinin Dihydroartemisinin is widely used as an intermediate in the preparation of other artemisinin-derived antimalarial drugs, recommended as the first-line anti-malarial drug with low toxicity. Dihydroartemisinin has anticancer activity, it inhibited cell proliferation via AKT/GSK3β/cyclinD1/ERK pathway and induced apoptosis is associated with inhibition of Sarco/Endoplasmic reticulum Calcium ATPase activity in colorectal cancer. |
CFN93796 | Dihydrobaicalein Dihydrobaicalein is a natural product from Scutellaria baicalensis Georgi. |