Hot Products
| Catalog No. | Information |
| CFN90386 | Jaceosidin Jaceosidin has immunosuppressive, anti-oxidative, anti-inflammatory, and anticancer activities, it is also a microglial inhibitor with anti-neuroinflammation activity. Jaceosidin modulates the ERK/ATM/Chk1/2 pathway, leading to inactivation of the Cdc2-cyclin B1 complex, followed by G2/M cell cycle arrest in endometrial cancer cells. Jaceosidin inhibits T cell proliferation and activation, which is closely associated with its potent down-regulation of the IFN-γ/STAT1/T-bet signaling pathway. |
| CFN00375 | Jacobine Jacobine induces significant dose-dependent DNA-DNA interstrand cross-linking over the entire range of doses. It was catalyzed by guinea pig hepatic glutathione-S-transferase enzymes in in vitro experiments. |
| CFN00461 | Jacobine N-oxide |
| CFN00376 | Jacoline Jacoline, jaconine, jacobine, and jacozine, the hepatotoxic alkaloids, are potentially carcinogenic, mutagenic, and teratogenic and may pose health hazards to the human consumer. |
| CFN00377 | Jaconine Jaconine, jacoline,jacobine, and jacozine, the hepatotoxic alkaloids, are potentially carcinogenic, mutagenic, and teratogenic and may pose health hazards to the human consumer. |
| CFN92274 | Jacoumaric acid Jacoumaric acid is a lead molecule from the library or database of natural compounds as a HIV-1 protease inhibitor. |
| CFN95434 | Jacquilenin Jacquilenin has anti-inflammatory activity |
| CFN97510 | Jangomolide Jangomolide, a novel limonoid from flacourtia jangomas. |
| CFN98493 | Jatrorrhizine Jatrorrhizine has neuroprotective, antioxidative, anti-inflammatory, antihypercholesterolemic, and anti-hyperglycemia effects.Jatrorrhizine is expected to be developed as a new gastric prokinetic drug, it is metabolized by human CYP1A2 and multiple UGT1A isoforms. It has inhibitory activities against the expression of inducible NO syntase (iNOS) and cyclooxygenase-2 (COX-2), and can improve the utilization and excretion of cholesterol by up-regulating the mRNA and protein expression of LDLR and CYP7A1. |
| CFN98108 | Jatrorrhizine Hydrochloride Jatrorrhizine hydrochloride has lipid lowering effects, it can ameliorate hyperlipidemia via the suppression of lipogenesis and the enhancement of lipid oxidation in the liver. It exhibits a potent inhibitory effect toward neuraminidase of the H7N9 (N9) avian influenza virus, it also can potentiate the neuraminidase inhibitory effect of oseltamivir towards H7N9 influenza. Jatrorrhizine hydrochloride is a potential new antimelanoma drug candidate, can inhibit the proliferation and neovascularization of C8161 metastatic melanoma cells with low toxicity. |
