Hot Products
| Catalog No. | Information |
| CFN90834 | Kuwanon A |
| CFN92320 | Kuwanon E Kuwanon E inhibited cholinesterase enzyme in a dose-dependent manner with K_i values ranging between 3.1 and 37.5 μM and between 1.7 and 19.1 μM against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes, respectively. Kuwanon E also inhibited the production of MUC5AC mucin induced by PMA from NCI-H292 cells,. |
| CFN93278 | Kuwanon G Kuwanon G is a specific antagonist for the GRP-preferring receptor and can be useful for studying the physiological and pathological role of GRP. Kuwanon G as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. Kuwanon G also shows acetylcholinesterase (AChE) and butyrylcholinesterase(BChE) inhibitory activities, it may be a promising candidate for preventive and therapeutic agents for Alzheimer's disease. Kuwanon G has anti-inflammatory, antibacterial, and allergic asthma activities, it can attenuate atherosclerosis through inhibiting foam cell formation and inflammatory response, it is a potent inhibitor of Mycobacterium tuberculosis protein tyrosine phosphatase B. |
| CFN90835 | Kuwanon H Kuwanon H, and possibly kuwanon G also, are specific antagonists for the gastrin-releasing peptide (GRP) -preferring receptor and can be useful for studying the physiological and pathological role of GRP. |
| CFN90072 | Kynurenic acid Kynurenic acid, a natural metabolite of tryptophan via the kynurenine pathway, is a broad-spectrum excitatory amino acid antagonist; It proved to be an antagonist at NMDA, kainate and AMPA receptors.Kynurenic acid is the endogenous α7 nicotinic acetylcholine receptor antagonist, it has an immunomodulating effect, it can modulate amyloid-β-induced inflammation in BV-2 microglial cells. |
| CFN70231 | L-(-)-Malic acid Reference standards. |
| CFN70193 | L(-)-Tryptophan Reference standards. |
| CFN91629 | L-(+)-Ergothioneine Ergothioneine is synthesized by certain bacteria and fungi. It is generally considered an antioxidant, but also has anti-inflammatory, cyto-protective, liver-protecting properties. |
| CFN70213 | L-(+)-Tartaric acid Reference standards. |
| CFN00121 | Lactacystin Lactacystin is a selective UPS inhibitor recently used to destroy dopamine (DA) neurons in animal models of Parkinson's disease (PD); marked differences in the rotational response to apomorphine and l-DOPA suggest different mechanisms of neurodegeneration evoked by Lactacystin and 6-OHDA. Lactacystin induces cell death and α-synuclein-positive inclusions in cytoplasm, it has diversified killing effects on gastric cancer cells, the mechanism may be related to induce the apoptosis by downregulation of nuclear factor kappa B viability. |
