Hot Products
| Catalog No. | Information |
| CFN92120 | Wilfornine A Wilfornine A is a natural product from Schisandra sphenanthera. |
| CFN92083 | Wilforol A Wilforol A is a natural product from Tripterygium wilfordii Hook. f. |
| CFN99802 | Wilforol C Reference standards. |
| CFN92105 | Wilfortrine Wilfortrine can induce liver cancer cell HepG2 apoptosis, but with no effect on the cell cycle, mainly by promoting Bax expression and inhibiting anti-apoptotic protein Bcl-2 expression. The combined treatment using wilfortrine and paclitaxel can inhibit proliferation and invasion of liver cancer cells via down-regulating Bcl-2 and up-regulating Bax, with better efficacy than single use of either drug. Wilfortrine and euonine (40.80 mg/(kg.d) x 4d ip) show marked depressant effects on humoral mediated immunity using the hemolysin reaction as indices. |
| CFN98624 | Wilsonine Standard reference |
| CFN91895 | Withaferin A Withaferin A(WFA) has anti-inflammatory, anti-oxidant, immune modulatory, cardioactive, antithrombotic and central nervous system effects, it could act as an anti-fibrotic compound against fibroproliferative diseases, including, but not limited to, cardiac interstitial fibrosis. WFA is a proteasomal inhibitor promotes healing after injury and exerts anabolic effect on osteoporotic bone. WFA is a potent breast cancer anti-metastatic agent and the anti-metastatic activity of WFA is, at least in part, mediated through its effects on vimentin and vimentin ser56 phosphorylation; it induces p53-dependent apoptosis by repression of HPV oncogenes and upregulation of tumor suppressor proteins in human cervical cancer cells, it can be exploited as a potent therapeutic agent for the treatment and prevention of cervical cancer without deleterious effects. |
| CFN91964 | Withanolide A Withanolide A extends the lifespan in human EGFR-driven cancerous Caenorhabditis elegans. Withanolide A may serve as potential neuroprotective agent due to inhibition of MAPK family proteins and activation of PI3K/Akt signaling, it plays an important role in central muscarinic receptor functional balance and activation of antioxidant system in the cerebral cortex of temporal lobe epileptic condition. Withanolide A shows anticancer activity against the SK-Br-3 cells. |
| CFN91963 | Withanolide B Reference standards. |
| CFN96435 | Withanolide C Withanolide C is a natural product from Physali alkekengi. |
| CFN70327 | Withanone Withanone can affords protection against NMDA-induced excitotoxicity in neuron-like cells, it may serve as potential neuroprotective agent, it shows promise in Alzheimer's disease treatment because of cognitive benefits. Withanone as a potential candidate molecule in cancer therapy. |
