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Screening Libraries
MCP-1 Inhibitor Library
A unique collection of 9 MCP-1 Inhibitor Library for high throughput screening (HTS), high content screening (HCS) and New drug research
Cat. Size Price Stock
T100721mg/well * 9 CompoundsInquiry In stock
Contact Us
T10072100uL/well (10mM solution) * 9 CompoundsInquiry In stock
*You can select compounds, quantities, format (dry/solid or DMSO) and plate map to meet your specific requirement.
Contact Us
E-mail manager@chemfaces.com
Tel (0086)-27-8423-7683
Shelf Life (0086)-27-84254680
ManufacturerWuhan ChemFaces Biochemical Co., Ltd.
Package & Storage
Container 96 Well Format Sample
Storage Protected from air and light, refrigerate or freeze(2-8 °)
Shelf Life 24 months (2-8 °)
Intended UseFor research use only. Not for human use. Not sell to patients
Description & Advantages
1. The products in the ChemFaces screening libraries are all from plants.
2. The biological activities or pharmacological activities of all the ChemFaces products are derived from the databases of all over the world the latest literatures, you can according to the product manuals on our website to access the relevant literatures, hope that our informations can give some inspirations and help to your research.
3.The collections of unique natural products, which include antioxidants, anti-inflammatory, antibacterial, anticancer, and ect. Can be used for high throughput screening (HTS) and high content screening (HCS), is to help you carry out new drug screening, the emergence of new indications and other professional tools.
4.Structurally diverse, medicinally active, and cell permeable, NMR and HPLC validated to ensure high purity.
5. ChemFaces offers customized bioactive screening libraries , whereby you choose the specific compounds you want in the library, the quantities, plate map, concentration, and format (dry/solid or DMSO solution).
Natural Products
Catalog No. Information
CFN99115 6,7-Dihydroxycoumarin

6,7-Dihydroxycoumarin(Esculetin) has various biological and pharmaceutical properties including anti-edema, anti-inflammatory, anti-tumour, hepatoprotective, anti-osteoarthritis and anti-rheumatoid arthritis effects. It inhibits lipoxygenases (LOs), p42/44 MAPK activation, PI3-kinase activation, as well as NF-kappaB and AP-1 activation, it exhibits competitive inhibition against the oxidation of 3-(3,4-dihydroxyphenyl)- alanine by mushroom, the IC50 value of is 43 microM.
CFN98597 Theaflavin

Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase, which has anti-inflammatory, antioxidative, anti-mutagenic, anti-HSV-1, and anti-carcinogenic properties. Theaflavin is active in the prevention of fatty liver and obesity, it can significantly reduce lipid accumulation, suppress fatty acid synthesis, and stimulate fatty acid oxidation. Theaflavin inhibits LPS-Induced IL-6, MCP-1, and ICAM-1 expression in bone marrow-derived macrophages through the blockade of NF-κB and MAPK signaling pathways; it also protects nigral dopaminergic neurons against chronic MPTP/probenecid induced Parkinson's disease.
CFN90237 Gardenoside

Gardenoside has hepatoprotective, pain‑relieving, and anti-mastitis effects. it may be a potential therapeutic herb against NASH by suppressed supernatant inflammatory cytokine production and intracellular NFkB activity. Gardenoside may be considered potential drug candidates that target P2X3 and P2X7 purine receptors.
CFN90509 Berberrubine

Berberrubine possesses diverse pharmacological activities, including glucose-lowering, lipid-lowering, anti-inflammatory, and anti-tumor effects. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expression of the cells stimulated with IL-1beta or TNF-alpha.
CFN90554 Caffeic acid phenethyl ester

Caffeic acid phenethyl ester is a potent and specific inhibitor of NF-κB activation, and also displays neuroprotective, antioxidant, immunomodulatory and antiinflammatory activities; it also has potential beneficial effects on the wound healing of nasal mucosa in the rat.Caffeic acid phenethyl ester has potential preventive effects on myringosclerosis development after myringotomy and ventilation tube insertion.
CFN90606 Naringenin chalcone

Naringenin chalcone has antiallergic, anti-inflammatory ,and anti-asthmatic properties, it inhibits the production of proinflammatory cytokines in the interaction between adipocytes and macrophages, and improves adipocyte metabolic functions and exerts insulin-sensitizing effects by activating an adiponectin-related pathway.
CFN93165 Stearic Acid

Stearic Acid and its derivatives have been used as gelators in food and pharmaceutical gel formulations. Stearic Acid is a potent phosphatase 1B inhibitor, possibly causing an enhancement in the insulin receptor signaling to stimulate glucose uptake into adipocytes. Stearic Acid leads to dramatically reduced visceral fat likely by causing the apoptosis of preadipocytes, it also can reduce metastatic tumor burden.
CFN93168 Linoleic acid

Essential fatty acid. Prostaglandin precursor.Linoleic acid could be involved in the inflammatory response through stimulation of the neutrophil chemokine, IL-8.
CFN96233 Euphohelioscopin A

Euphohelioscopin A, an activator of protein kinase C (PKC), it inhibits proliferation and induces differentiation of the myeloid leukemia cell lines THP-1 and HL-60. Euphohelioscopin A has anti-inflammary activity, it exhibits moderate inhibitory activity on the release of cytokine TNF-α (IC50 = 23.7 ± 1.7 uM), IL-6 (IC50 = 46.1 ± 1.1 uM) and chemokine MCP-1 (IC50 = 33.7 ± 3.8 uM) in lipopolysaccharide (LPS) induced RAW 264.7 macrophages without notable cytotoxicity (IC50 > 80 uM).