Screening Libraries
| Cat. | Size | Price | Stock | |
| P20416 | 1mg/well * 11 Compounds | Inquiry | In stock | Contact Us |
| P20416 | 100uL/well (10mM solution) * 11 Compounds | Inquiry | In stock |
| manager@chemfaces.com | |
| Tel | (0086)-27-8423-7683 |
| Shelf Life | (0086)-27-84254680 |
| Manufacturer | Wuhan ChemFaces Biochemical Co., Ltd. |
| Container | 96 Well Format Sample |
| Storage | Protected from air and light, refrigerate or freeze(2-8 °) |
| Shelf Life | 24 months (2-8 °) |
| Intended Use | For research use only. Not for human use. Not sell to patients |
| 1. The products in the ChemFaces screening libraries are all from plants. |
| 2. The biological activities or pharmacological activities of all the ChemFaces products are derived from the databases of all over the world the latest literatures, you can according to the product manuals on our website to access the relevant literatures, hope that our informations can give some inspirations and help to your research. |
| 3.The collections of unique natural products, which include antioxidants, anti-inflammatory, antibacterial, anticancer, and ect. Can be used for high throughput screening (HTS) and high content screening (HCS), is to help you carry out new drug screening, the emergence of new indications and other professional tools. |
| 4.Structurally diverse, medicinally active, and cell permeable, NMR and HPLC validated to ensure high purity. |
| 5. ChemFaces offers customized bioactive screening libraries , whereby you choose the specific compounds you want in the library, the quantities, plate map, concentration, and format (dry/solid or DMSO solution). |
| Catalog No. | Information |
| CFN99103 | Rosmarinic acid Rosmarinic acid has antiviral, antibacterial, antiinflammatory, neuroprotective, anticancer, anti-lipid peroxidative, apoptotic,and antioxidant activities. It is used for food preservation, and to treat peptic ulcers, arthritis, cataract, cancer, rheumatoid arthritis, bronchial asthma, and several human neurodegenerative diseases caused by oxidative stress. Rosmarinic acid has the ability to block complement fixation, inhibit lipoxygenase and cyclooxygenase activity and inhibit the expression of CCL11 and CCR3 by suppressing the IKK-β activity in NF-κB activation signaling. It inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively. |
| CFN98565 | Luteolin-7-O-glucoside Luteolin-7-O-glucoside has cardioprotective, anti-asthmatic, anticancer, anti-inflammatory, and antioxidative activities, it can suppress leukotriene C(4) production and degranulation by inhibiting the phosphorylation of mitogen activated protein kinases and phospholipase Cγ1 in activated mouse bone marrow-derived mast cells.Luteolin-7-O-glucoside modulated the Nrf2/MAPK/ PTEN/Akt /ERK/AP-1/PI3K-Akt signaling pathways, it suppressed the expression of β-catenin. |
| CFN98123 | L-Menthol Menthol is used in analgesic balms and also in foods and oral hygiene products for its fresh cooling sensation, menthol enhances cooling by interacting with the cold-sensitive thermoTRP channel TRPM8. L-Menthol has antiperistaltic and anti-inflammatory effects, clinical trials investigating the potential therapeutic efficacy of L-menthol for treatment of chronic inflammatory disorders such as bronchial asthma, colitis and allergic rhinitis seem worthwhile, it sprayed on the gastric mucosa significantly suppresses peristalsis with minimal adverse drug reactions during upper GI endoscopy. |
| CFN93286 | Pulegone Pulegone is a fragrance and flavour ingredient. Pulegone has cytotoxicity followed by regenerative cell proliferation is the MOA for Pulegone-induced urothelial tumors in female rats. Pulegone induces a verapamil-sensitive psychostimulant effect that appears to independ on the opening of L-type calcium channels. |
| CFN93280 | Menthone Menthone has anti-inflammary activity, it can suppress the lipopolysaccharide (LPS)-induced proinflammatory cytokines, interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha), as well as nuclear factor kappaB (NF-kappaB) activity induced by LPS and other inflammatory agents. Menthone and menthol enhances the skin permeability by disordering the ordered organization of SC lipids and extracts part of SC lipids. |
| CFN99656 | p-Menthane-1,3,8-triol Reference standards. |
| CFN99160 | DL-Menthol DL-Menthol has short term toxicity in rats, it plays a role in the induction of surgical anesthesia in fishes, related at least in part to the activation of GABAA receptors, and of rapid movement possibly via cold nociceptors. |
| CFN98127 | (+)-Isopulegol |
| CFN98126 | Isopulegol Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possibly related to positive modulation of benzodiazepine-sensitive GABAA receptors and to antioxidant properties.Isopulegol presents significant gastroprotective effects in both ethanol- and indomethacin-induced ulcer models, which appear to be mediated, at least in part, by endogenous prostaglandins, K(ATP) channel opening, and antioxidant properties. |
| CFN98125 | D-Menthol Menthol is a common compound in pharmaceutical and commercial products and a popular additive to cigarettes, it attenuates α7 mediated Ca 2+ transients in the cell body and neurite, suggests that menthol inhibits α7-nACh receptors in a noncompetitive manner. Menthol has cooling sensation in the skin, by chemically triggering the cold-sensitive TRPM8 receptors. Menthol has analgesic property, it acts as a noncompetitive antagonist of the 5-HT3 receptor. |
