Tryptanthrine | CAS:13220-57-0 | Manufacturer ChemFaces

Tryptanthrine

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $8.9 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Tryptanthrin shows antimycobacterial and antifungal activity as well as anti-proliferative activity.

Targets:

Antifection

In vitro:

Planta Medica, 2012, 78(11):1284-1284.

Synthesis and determination of antimycobacterial activity of tryptanthrine, vasicine, vasicinone and derivatives thereof.[Reference: WebLink]

METHODS AND RESULTS:
We describe the first application of the Niementowski quinazoline synthesis for the synthesis of vasicinone 3 (Fig.1), an alkaloid from Adhatoda vasica, a traditionally used plant in India for the treatment of respiratory diseases such as asthma and tuberculosis.
CONCLUSIONS:
This straightforward 2-step synthesis is an attractive basis for further medicinal chemistry work on vasicinone. Vasicine, vasicinone, deoxyvasicinone and deoxyvasicine were tested against Mycobacterium vaccae, a non-pathogenic mycobacterium closely related to Mycobacterium tuberculosis. Tryptanthrin, a related indoloquinazolinone from Strobilanthes cusia, showed antimycobacterial and antifungal activity as well as anti-proliferative activity.

Tryptanthrine Description

Source:	The leaves of Strobilanthes cusia
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Tryptanthrine
Price:	$30 / 20mg
CAS No.:	13220-57-0
Catalog No.:	CFN70056
Molecular Formula:	C₁₅H₈N₂O₂
Molecular Weight:	248.2 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The leaves of Strobilanthes cusia
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Alkaloids Compound Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	4.029 mL	20.145 mL	40.2901 mL	80.5802 mL	100.7252 mL
5 mM	0.8058 mL	4.029 mL	8.058 mL	16.116 mL	20.145 mL
10 mM	0.4029 mL	2.0145 mL	4.029 mL	8.058 mL	10.0725 mL
50 mM	0.0806 mL	0.4029 mL	0.8058 mL	1.6116 mL	2.0145 mL
100 mM	0.0403 mL	0.2015 mL	0.4029 mL	0.8058 mL	1.0073 mL

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CFN70186	trans-2-Hexen-1-al	6728-26-3	98.1	C₆H₁₀O
CFN92602	Neobritannilactone B	886990-00-7	248.3	C₁₅H₂₀O₃