Bioactive Products
| A unique collection of 51 Anti-platelet aggregation natural compounds | ||
| Catalog No: | B24 | Anti-platelet-aggregation Compound Library Screening Details |
| Size: | 1mg/well * 51 Compounds 2mg/well * 51 Compounds | |
| Cat. No. | Information |
| CFN93212 | Panaxynol Panaxynol is the most potent antiplatelet agent in ginseng and its mechanism of action is chiefly due to the inhibition of thromboxane formation. Panaxynol has neuroprotective, and anti-proliferative effects, it induces neurite outgrowth in PC12D cells via cAMP- and MAP kinase-dependent mechanisms, and protects cortical neurons from ischemia-like injury by up-regulation of HIF-1alpha expression and inhibition of apoptotic cascade. Panaxynol has inhibitory effects on the proliferation of human pancreatic cancer cell PANC-1through inhibiting cell division and down-regulating Ki67 expression. |
| CFN90927 | Hydroxytyrosol acetate Hydroxytyrosol acetate has antibacterial, neuroprotective , antioxidant and anti-inflammatory effects, it can enhance the fluorescent intensity of DNA binding molecules and mediated supercoiled DNA relaxation. Hydroxytyrosol acetate can improve the oxidative events and return pro-inflammatory proteins expression to basal levels probably through JAK/STAT, MAPKs and NF-κB pathways. Hydroxytyrosol acetate and polyphenols hydroxytyrosol administered orally can inhibit platelet aggregation in rats and that a decrease in thromboxane synthesis along with an increase in nitric oxide production contributed to this effect. |
| CFN95004 | Decuroside I Decuroside I shows weak inhibiting activity against the primary and secondary wave aggregation of human platelet. |
| CFN90831 | Galloylpaeoniflorin Galloylpaeoniflorin exhibits anticomplement effects, it reveals a more pronounced radical scavenging effect than a-tocopherol. Galloylpaeoniflorin can take part in improving blood circulation by inhibiting ether platelet aggregation and/or blood coagulation. Galloylpaeoniflorin exhibits good activity on acute lung injury. |
| CFN96210 | 1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one 1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one shows strong inhibition of collagen-induced, arachidonic acid-induced, and adenosine diphosphate-induced platelet aggregation of human whole blood. |
