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    Natural Products
    Decuroside I
    Information
    CAS No. 96638-79-8 Price $318 / 5mg
    Catalog No.CFN95004Purity>=98%
    Molecular Weight570.6Type of CompoundCoumarins
    FormulaC26H34O14Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
    Citing Use of our Products
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $365.7 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
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  • University of Beira Interior (Portugal)
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    Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Anti-platelet aggregation Compound Library
  • Coumarins Compound Library
  • PAFR Inhibitor Library
  • Biological Activity
    Description: Decuroside I shows weak inhibiting activity against the primary and secondary wave aggregation of human platelet.
    Targets: PAFR
    In vitro:
    Planta Med.,1986, 52(02):135-8.
    Studies on coumarins of a Chinese drug [Pubmed: 3725933]

    METHODS AND RESULTS:
    Three kinds of new coumarin-glycosides, Decuroside I ( 1), Decuroside II ( 2), Decuroside III ( 3), which were isolated from the N-butanol extracts of the crude drug Zi-Hua Qian-Hu, the root of PEUCEDANUM DECURSIVUM Maxim. (Umbelliferae), were elucidated to be nodakenetin-4′- O-β-gentiobiose, nodakenetin-4′- Oβ-isomaltose and nodakenetin-4′- O-β-maltose, respectively, by the methods of chemical and spectral analysis. These three new compounds as well as Decuroside IV ( 4), decuroside V ( 5) and nodakenin ( 6) which were also isolated from Zi-Hua Qian-Hu were tested on human platelet aggregation induced by 2 μM ADP.
    CONCLUSIONS:
    Among these coumarin-glycosides, 3 and 4, showed the strongest inhibiting activity against the primary and secondary wave aggregation of human platelet. 1 and 2 had a less inhibiting effect or none at all, and 5 was rather promotive against the primary wave aggregation.
    Decuroside I Description
    Source: The herbs of Peucedanum decursivum Maxim.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.7525 mL 8.7627 mL 17.5254 mL 35.0508 mL 43.8135 mL
    5 mM 0.3505 mL 1.7525 mL 3.5051 mL 7.0102 mL 8.7627 mL
    10 mM 0.1753 mL 0.8763 mL 1.7525 mL 3.5051 mL 4.3814 mL
    50 mM 0.0351 mL 0.1753 mL 0.3505 mL 0.701 mL 0.8763 mL
    100 mM 0.0175 mL 0.0876 mL 0.1753 mL 0.3505 mL 0.4381 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.