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Bioactive Products
Anticancer Compound Library
A unique collection of 674 anticancer natural compounds for high throughput screening (HTS) and New anticancer drug research
Catalog No: B91 Anticancer Compound Library
Screening Details
Size: 1mg/well * 674 Compounds
2mg/well * 674 Compounds
Cat. No. Information
CFN99689 Yunnancoronarin A

Yunnancoronarin A shows cytotoxicity against the lung adenocarcinoma cells A549 and leukemia cells K562, with the IC(50) value of 2.20 microM.
CFN99806 Epifriedelanol

Epifriedelanol has antitumor activity, it can reduce cellular senescence in human primary cells and may be used to develop dietary supplements or cosmetics that modulate tissue aging or aging-associated diseases. Epifriedelanol exhibits significant inhibition of NF-kappa B, it may be used to treat asthma.
CFN99810 2-Hydroxy-3-methylanthraquinone

2-Hydroxy-3-methylanthraquinone enhances apoptosis of U937 cells,in part,through activation of p-p38MAPK and downregulation of p-ERK1/2; triggers caspase-3 activation mediated apoptotic induction.
CFN99814 Rhoifolin

Rhoifolin possesses a variety of significant biological activities including antioxidant, anti-inflammatory, antimicrobial, hepatoprotective and anticancer effects, it may be beneficial for diabetic complications through its enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4 translocation. Rhoifolin has a radioprotective effect against radiation-induced decrease of blood platelets and cardiac biochemical lesions in whole body irradiated mice.
CFN99815 Ganoderic acid DM

Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1), this suppression leads to the inhibition of dendritic cell-specific transmembrane protein (DC-STAMP) expression and reduces osteoclast fusion. Ganoderic acid DM has shown toxicity to both androgen-dependent and independent prostate cancer cells with reduced osteoclastogenesis in late stage metastatic disease, it may an alternative agent for the treatment of advanced prostate cancer.