Bioactive Products
| A unique collection of 81 Cardioprotective natural compounds for high throughput screening (HTS) and high content screening (HCS). | ||
| Catalog No: | Bb1313 | Cardioprotective Compound Library Screening Details |
| Size: | 1mg/well * 81 Compounds 2mg/well * 81 Compounds | |
| Cat. No. | Information |
| CFN92802 | 14-Deoxyandrographolide 14-Deoxyandrographolide has hepatoprotective activity, mediates activation of adenylate cyclase-cAMP signaling leading to up-regulation of cNOS, may provide a promising approach in the prevention of liver diseases during chronic alcoholism. It desensitizes hepatocytes to TNF-alpha-mediated apoptosis through the release of TNFRSF1A. |
| CFN96102 | Moracin O Moracin O shows significant neuroprotective, and analgesic activities, it also has a strong protective influence against doxorubicin-induced cardiomyopathy in H9c2 cells with the EC50 value of 4.5 ± 1.3 uM. Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia. |
| CFN90290 | Oxysophoridine Oxysophoridine has a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms; it may be a potential neuroprotective agent for cerebral ischemia injury, that the effect may be due to its ability to inhibit oxidative stress and expression of the N-methyl-D-aspartate receptor subunit NR1.Oxysophoridine ameliorates cardiac damage in a rat model of AMI and that this cardioprotection may be linked with its anti-oxidative, anti-apoptotic and anti-inflammatory properties. |
| CFN90617 | Hirsutine Hirsutine has anticancer, cardioprotective, anti‑hypertensive and anti-arrhythmic activities, it also has vasodilatation activity, the mechanism is related to blockade of Ca2+ influx through L-type Ca2+ channels and inhibition of intracellular Ca2+ release may have no relationship with K+ channels. Hirsutine reduces the production of various neurotoxic factors in activated microglial cells and possesses neuroprotective activity in a model of inflammation-induced neurotoxicity. |
| CFN90647 | Calceolarioside B Calceolarioside B has anti-proliferation property. |
