Vachellia farnesiana, also known as Acacia farnesiana, commonly known as Needle Bush, is so named because of the numerous thorns distributed along its branches. The native range of V. farnesiana is uncertain. While the point of origin is Mexico and Central America the species has a pantropical distribution incorporating Northern Australia and Southern Asia.
Vachellia. farnesiana has been used in Colombia to treat malaria, and it has been confirmed in the laboratory that extract from the tree bark and leaves is effective against the malarial pathogen Plasmodium falciparum. Indigenous Australians have used the roots and bark of the tree to treat diarrhea and diseases of the skin.
The following compounds are said to be in Vachellia farnesiana: 5-MeO-DMT; Tryptamine; β-methyl-phenethylamine, flower. Ether extracts about 2-6% of the dried leaf mass.[23] Alkaloids are present in the bark.