Psoralea corylifolia (Babchi) is an important plant in the Indian Ayurveda and Tamil Siddha systems of medicine, and also Chinese medicine. The seeds of this plant contain a variety of coumarins including psoralen. An extract of the plant's fruit Fructus psoraleæ has been shown to act as a norepinephrine-dopamine reuptake inhibitor.
The effect of aqueous and alcohol extracts of the leaves and seeds of Psoraleacorylifolia, on the spontaneous movements of both the whole worm and the nerve muscle preparation of Setaria cervi and on the survival of microfilariae in vitro was studied.
P. corylifolia extract contains a number of bioactive compounds that are the molecular basis of its action, including flavonoids (neobavaisoflavone, isobavachalcone, bavachalcone, bavachinin, bavachin, corylin, corylifol, corylifolin and 6-prenylnaringenin), coumarins (psoralidin, psoralen, isopsoralen and angelicin) and meroterpenes (bakuchiol and 3-hydroxybakuchiol).