- ChemFaces is a professional high-purity natural products manufacturer.
- Product Intended Use
- 1. Reference standards
- 2. Pharmacological research
- 3. Inhibitors
1,3,9-Trimethyluric acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
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Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / Inquiry |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
- Front Aging Neurosci.2019, 11:230
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- Inflammation.2024, 02034-1.
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- Int J Mol Sci.2020, 21(6):2190.
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Our products had been exported to the following research institutions and universities, And still growing.
- Max-Planck-Insitut (Germany)
- Monash University Sunway Campus (Malaysia)
- Amity University (India)
- University of Otago (New Zealand)
- Charles Sturt University (Denmark)
- Chulalongkorn University (Thailand)
- Utrecht University (Netherlands)
- Chiang Mai University (Thailand)
- University of Liège (Belgium)
- University of Padjajaran (Indonesia)
- Universiti Kebangsaan Malaysia (Malaysia)
- More...
- Plant Physiol Biochem.2021, 160:166-174.
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Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
|
| Description: |
1,3,9-Trimethyluric acid exhibits in vitro cytotoxic activity against breast cancer (MCF-7), human neuroblastoma (SHSY5Y), human non-small cell lung cancer (A549) and human liver cancer (HEPG2) with IC50 value in the range of 1-3 uM. 1,3,9-Trimethyluric acid also shows promising anti-inflammatory effects in LPS induced murine macrophage J774 in vitro models in the concentration range of 100-1000 nM.
|
| Targets: |
Immunology & Inflammation related |
| In vitro: |
| Int.J.Sci. Res.,2017,6(1):13-17. | | Isolation and X-ray crystal structure of 1,3,9 trimethyl purine derivative having cytotoxic activities from marine sponge Amphimedon viridis (Duchassaing & Michelotti,1864) [Reference: WebLink] |
METHODS AND RESULTS:
A new purine derivative 1,3,9-Trimethyluric acid (1) was isolated from the marine sponge Amphimedon viridis and structure were confirmed by X-ray crystallography data.
CONCLUSIONS:
Compound 1 exhibited in vitro cytotoxic activity against breast cancer (MCF-7), human neuroblastoma (SHSY5Y), human non-small cell lung cancer (A549) and human liver cancer (HEPG2) with IC50 value in the range of 1-3 μM and also showed promising anti-inflammatory effects in LPS induced murine macrophage J774 in vitro models in the concentration range of 100-1000 nM. |
|
1,3,9-Trimethyluric acid Description
| Source: |
The culture of the marine sponge Amphimedon viridis. |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
4.7576 mL |
23.788 mL |
47.576 mL |
95.152 mL |
118.94 mL |
| 5 mM |
0.9515 mL |
4.7576 mL |
9.5152 mL |
19.0304 mL |
23.788 mL |
| 10 mM |
0.4758 mL |
2.3788 mL |
4.7576 mL |
9.5152 mL |
11.894 mL |
| 50 mM |
0.0952 mL |
0.4758 mL |
0.9515 mL |
1.903 mL |
2.3788 mL |
| 100 mM |
0.0476 mL |
0.2379 mL |
0.4758 mL |
0.9515 mL |
1.1894 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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