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    Natural Products
    11-Hydroxyhumantenine
    11-Hydroxyhumantenine
    Information
    CAS No. 122590-04-9 Price
    Catalog No.CFN97998Purity>=98%
    Molecular Weight370.5Type of CompoundAlkaloids
    FormulaC21H26N2O4Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Description: Standard reference
    11-Hydroxyhumantenine Description
    Source: The herbs of Gelsemium elegans
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
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    IF=22.415(2019)

    PMID: 32004475

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    IF=14.548(2019)

    PMID: 29149595

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    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.6991 mL 13.4953 mL 26.9906 mL 53.9811 mL 67.4764 mL
    5 mM 0.5398 mL 2.6991 mL 5.3981 mL 10.7962 mL 13.4953 mL
    10 mM 0.2699 mL 1.3495 mL 2.6991 mL 5.3981 mL 6.7476 mL
    50 mM 0.054 mL 0.2699 mL 0.5398 mL 1.0796 mL 1.3495 mL
    100 mM 0.027 mL 0.135 mL 0.2699 mL 0.5398 mL 0.6748 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Helvetica Chimica Acta.2009 Sep;92(9):1889–1894.
    Two New 11-Hydroxy-Substituted Gelsedine-Type Indole Alkaloids from the Stems of Gelsemium elegans.[Reference: WebLink]

    METHODS AND RESULTS:
    Two new 11-hydroxy-substituted gelsedine-type indole alkaloids, named 11,14-dihydroxygelsenicine (1) and 11-hydroxygelsenicine (2), together with six known alkaloids, i.e., koumine, gelsemine, 14-hydroxygelsenicine, 11-Hydroxyhumantenine, gelsenicine, and (19Z)-akuammidine, were isolated from the EtOH extract of the stems of Gelsemium elegansbenth. Their structures were determined mainly by means of spectroscopic analyses including HR-ESI-MS and 2D-NMR (HSQC, HMBC, 1H,1H-COSY).
    CONCLUSIONS:
    The configuration of 1 was confirmed by X-ray-diffraction analysis.