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    18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one
    18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one
    Information
    CAS No. 213329-46-5 Price
    Catalog No.CFN98065Purity>=98%
    Molecular Weight302.4 Type of CompoundDiterpenoids
    FormulaC19H26O3Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)
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    18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one Description
    Source: The barks of Pinus yunnanensis
    Biological Activity or Inhibitors: 1. 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one shows moderate cytotoxicity against a human lung carcinoma cell line.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.3069 mL 16.5344 mL 33.0688 mL 66.1376 mL 82.672 mL
    5 mM 0.6614 mL 3.3069 mL 6.6138 mL 13.2275 mL 16.5344 mL
    10 mM 0.3307 mL 1.6534 mL 3.3069 mL 6.6138 mL 8.2672 mL
    50 mM 0.0661 mL 0.3307 mL 0.6614 mL 1.3228 mL 1.6534 mL
    100 mM 0.0331 mL 0.1653 mL 0.3307 mL 0.6614 mL 0.8267 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one References Information
    Citation [1]

    Molecules. 2012 Aug 13;17(8):9716-27.

    Diterpenoids from the buds of Pinus banksiana Lamb.[Pubmed: 22890174]
    Three new diterpenoids, namely 7α-hydroxyabieta-8,11,13,15-tetraen-18-oic acid, 7β,15,18-trihydroxyabieta-8,11,13-triene, 13,15-dihydroxypodocarpa-8,11,13-triene, and 12 other known compounds were isolated from buds of Pinus banksiana Lamb. All these compounds, except for 7-oxodehydroabietinol, were isolated for the first time from this plant. Their structures were elucidated by detailed spectroscopic studies and comparison with published data. All isolated compounds were tested for cytotoxic and antibacterial activities. Overall, two compounds, 7-oxodehydroabietinol and 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one, showed moderate cytotoxicity against a human lung carcinoma cell line.