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20-Hydroxyaflavinine
20-Hydroxyaflavinine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 20-Hydroxyaflavinine
Price:
CAS No.: 116865-08-8
Catalog No.: CFN96981
Molecular Formula: C28H39NO2
Molecular Weight: 421.62 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The metabolites of the ascomycete fungus Tricladium sp.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: 20-Hydroxyaflavinine is a natural product from the metabolites of the ascomycete fungus Tricladium sp.
In vitro:
Chem Biodivers. 2011 Oct;8(10):1914-20.
Two new imidazolone-containing alkaloids and further metabolites from the ascomycete fungus Tricladium sp.[Pubmed: 22006720 ]

METHODS AND RESULTS:
Tricladins A and B (1 and 2, resp.), new imidazolone-containing alkaloids, together with five known metabolites, bacillamides A, B (3 and 4, resp.), 20-Hydroxyaflavinine (5), N-(2-phenylethyl)acetamide (6), and N(b)-acetyltryptamine (7), have been isolated from the crude extract of the ascomycete fungus Tricladium sp. The structures of 1 and 2 were elucidated primarily by NMR and MS methods.
CONCLUSIONS:
Compound 2 showed marginal cytotoxicity against MDA-MB-231 human breast cancer cells, whereas the known metabolite 4 displayed an inhibitory effect on HIV-1 replication in C8166 cells.
20-Hydroxyaflavinine Description
Source: The metabolites of the ascomycete fungus Tricladium sp.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3718 mL 11.859 mL 23.718 mL 47.4361 mL 59.2951 mL
5 mM 0.4744 mL 2.3718 mL 4.7436 mL 9.4872 mL 11.859 mL
10 mM 0.2372 mL 1.1859 mL 2.3718 mL 4.7436 mL 5.9295 mL
50 mM 0.0474 mL 0.2372 mL 0.4744 mL 0.9487 mL 1.1859 mL
100 mM 0.0237 mL 0.1186 mL 0.2372 mL 0.4744 mL 0.593 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Sinomenine

Catalog No: CFN99508
CAS No: 115-53-7
Price: $30/20mg
Deapi-platycodin D

Catalog No: CFN90472
CAS No: 78763-58-3
Price: $268/10mg
Spinosin

Catalog No: CFN99600
CAS No: 72063-39-9
Price: $80/20mg
Oxypeucedanin hydrate

Catalog No: CFN90557
CAS No: 2643-85-8
Price: $80/20mg
6-Gingerol

Catalog No: CFN99931
CAS No: 23513-14-6
Price: $50/20mg
Cyanidin-3-O-(6''-malonylglucoside...

Catalog No: CFN91864
CAS No: 171828-62-9
Price: $613/5mg
Rhapontigenin

Catalog No: CFN92607
CAS No: 500-65-2
Price: $118/20mg
Ganoderic acid K

Catalog No: CFN92057
CAS No: 104700-95-0
Price: $318/5mg
Phillygenin

Catalog No: CFN90511
CAS No: 487-39-8
Price: $118/20mg
11-Oxomogroside III

Catalog No: CFN92192
CAS No: 952481-53-7
Price: $318/10mg
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