ChemFaces is a professional high-purity natural products manufacturer.
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2. Pharmacological research
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More articles cited ChemFaces products.
Biochem Biophys Res Commun. 2017 Dec 16;Int J Mol Sci.2017 Nov 30;J Agric Food Chem.2018 Jan 10;New Zealand Journal of Forestry Sci.2014, 44:17Front Pharmacol. 2017 Apr 25;
Sci Rep. 2017 Jan 9;J Ethnopharmacol. 2017 Feb 2;FEMS Microbiol Lett. 2017 Jun 15;Srinagarind Medical JournalNo 1 (2017) J Nat Prod. 2017 Apr 28;
Jour. of Stored Pro & Postharvest Res.March 2016Academic JournalApr. 2014Phytochemistry2017 Jun;J Ethnopharmacol. 2017 Jan 20;
Our products had been exported to the following research institutions and universities, And still growing.
Chulalongkorn University (Thailand)University of Bonn (Germany)Cornell University (USA)Heinrich-Heine-University Düsse... (Germany)
Korea Intitute of Science and Te... (Korea)Universidad Miguel Hernández (Spain)Sri Ramachandra University (India)Utrecht University (Netherlands)
Northeast Normal University Chan... (China)Universidade Católica Portuguesa (Portugal)Institute of Tropical Disease Un... (Indonesia)
||3-Deoxyaconitine has toxicity. |
||The roots of Aconitum kusnezoffii Reichb.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi: 10.1016/j.phymed.2017.12.030.PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Acta Crystallogr Sect E Struct Rep Online. 2010 May 15;66(Pt 6):o1342. |
|3-Deoxyaconitine from the root of Aconitum Carmichaeli Debx.[Pubmed: 21579431]|
METHODS AND RESULTS:
3-Deoxyaconitine:8β-acet-oxy-14α-benzo-yloxy-N-ethyl-13β,15α-dihydr-oxy-1α,6α,16β-trimeth-oxy-4β-methoxy-methyl-eneaconitane), C(34)H(47)NO(10), is a typical aconitine-type C(19)-diterpenoid alkaloid, and was isolated from the roots of the Aconitum carmichaeli Debx. The mol-ecule has an aconitine carbon skeleton with four six-membered rings and two five-membered rings, whose geometry is similar to these observed in other C(19)-diterpenoid alkaloids; both of five-membered rings have the envelope configurations and the six-membered N-containing heterocyclic ring displays a chair conformation. Intra-molecular O-H⋯O hydrogen bonding occurs.
Weak inter-molecular C-H⋯O hydrogen bonding is observed in the crystal structure.
|Chinese Traditional Patent Medicine , 2011 , 33 (3) :479-482. |
|Determination of aconitine and 3-deoxyaconitine in fried samples of Aconitum pendulum Busch by HPLC[Reference: WebLink]|
|To analyze the influences on the contents of aconitine and 3-Deoxyaconitine in Aconitum pendulum Busch by different processing methods used in Tibetan medicine,Qiang medicine and Hui medicine,and to observe the relativity between processing and toxicity.|
METHODS AND RESULTS:
The determination was performed by HPLC,and Kromasil C18 column(250 mm×4.6 mm,5 μm) was used with the mobile phase being methanol:water:trieth-ylamine(95:5:0.3),flow rate was 1.0 mL/min,the column temperature was set at 25 ℃,detection wave-length was set at 235 nm.All the contents of aconitine and 3-Deoxyaconitine in A.pendulum Busch samples decreased after being fried.It showed that temperature was the main factor in decomposing the dibasic acid structures of aconitine and reducing toxicity.
All chromatograph peaks could be well separated,and the method is very stable.And among all the methods,the processing used in Tibetan medicine is much more scientific and effective.