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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Scientific World Journal....2014...Sci Rep.2015, 5:13194Korean J. of Food Sci. and Tech...2016...Evid Based Complement Alternat Me...2016...Molecules.2016, 21(6)The Korea Journal of Herbology...2016...Org Biomol Chem.2017, 15(31):6483-6492Int J Mol Sci.2017, 19(1)
Journal of Functional Foods...2017...Front Aging Neurosci.2018, 10:269International Food Research Journ...2018...Bioorg Med Chem.2018, 26(14):4201-4208Biol Pharm Bull.2018, 41(11):1645-1651Korean Journal of Pharmacognosy...2018...Eur J Pharmacol.2018, 832:96-103Front Immunol.2018, 9:2655
Clin Transl Oncol.2019, 10.1007Analytical methods2019, 11(6)Int J Mol Sci.2019, 20(11):E2734Molecules.2019, 24(19):E3417J Food Biochem.2019, 43(9):e12970Pharmacological Reports2020, 1-9Plant Growth Regulation...2020...
Our products had been exported to the following research institutions and universities, And still growing.
Kamphaengphet Rajabhat University (Thailand)Lund University (Sweden)University of Indonesia (Indonesia)The Vancouver Prostate Centre (... (Canada)
National Chung Hsing University (Taiwan)Melbourne University (Australia)University of Toronto (Canada)University of Liège (Belgium)
Calcutta University (India)University of South Australia (Australia)St. Jude Children Research Hosp... (USA)
Related Screening Libraries
|| 3-Oxotirucalla-7,24-dien-21-oic acid shows potent cytotoxicity against MCF-7 cell line.|
|Revista Brasileira de Farmacognosia.2014 Oct;24(5):561–564. |
|Cytotoxic tirucallane triterpenes from the stem of Luvunga scandens.[Reference: WebLink]|
METHODS AND RESULTS:
Two tirucallane triterpenes, namely flindissol (1) and 3-Oxotirucalla-7,24-dien-21-oic acid (2), were isolated from the dichloromethane extract of the stem of Luvunga scandens (Roxb.) Buch-Ham ex Wight & Arn, Rutaceae. This is the first report of their isolation from this plant. Their structures were constructed by high resolution mass and 2D NMR spectroscopic data. The cytotoxic potential of the two pure compounds 1 and 3-Oxotirucalla-7,24-dien-21-oic acid were determined by MTT assay against human breast adenocarcinoma cell line (MCF-7).
Compounds 1 and 3-Oxotirucalla-7,24-dien-21-oic acid showed potent cytotoxicity against MCF-7 cell line with IC50 values of 13.8 μM and 27.5 μM, respectively. This result suggested their potential activity as antitumor agents.
3-Oxotirucalla-7,24-dien-21-oic acid Description
||The leaves of Rubus alceaefolius
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Zhong Yao Cai. 2015 Jan;38(1):93-6. |
|Study on Chemical Constituents of Petroleum Ether Fraction from Rubus alceaefolius.[Pubmed: 26214876]|
|To investigate the chemical constituents of Rubus alceaefolius.
METHODS AND RESULTS:
Nine compounds were isolated and purified from the petroleum ether extract of 95% alcohol extract of Rubus alceaefolius by repeated column chromatography on silica, Sephadex LH-20 and structurally identified by spectral analysis.
The compounds were identified as chrysophanol(1), physcion (2), β-sitosterol(3), 3-oxotirucalla-7, 24-dien-21-oic acid(4), myricadiol(5), 19-α-hydroxy-3-acetyl-ursolic acid(6), N-benzoylphenylalaninyl-N-benzoylphenylalaninate(7), aurantiamide acetate(8) and euscaphic acid(9).
Compounds land 4~8 are isolated from this plant for the first time, and compounds 4 - 8 are found in plants of Rubus genus for the first time.