ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
Viruses. 2017 Oct 3;9(10). Acta Physiologiae PlantarumJanuary 2016, 38:7Journal of Life Science2017.2;Fitoterapia. 2018 Jan;J Pharm Biomed Anal. 2016 Jun 25;129:50-59.
Clin Exp Pharmacol Physiol.2015 Aug 1Molecules 2016, 21(6), 739;2016 Jun 14;21(6). Plant Cell Physiol.2018 Jan 1;Phytochemistry2017 Jun;Molecules.2013 Nov 14;18(11):14105-21.
Int. J. of Food Properties08 Feb 2017;Inflammation. 2015 Feb 6.Int J Mol Sci.2017 Nov 30;Chemistr of plant2016021195
Our products had been exported to the following research institutions and universities, And still growing.
Universidade Federal de Pernambu... (Brazil)University of Toronto (Canada)University of Fribourg (Switzerland)Medical University of South Caro... (USA)
University of Ioannina (Greece)Kyushu University (Japan)Stanford University (USA)Heidelberg University (Germany)
University of Melbourne (Australia)Indian Institute of Science (India)University of Pretoria (South Africa)
|| 3-Oxotirucalla-7,24-dien-21-oic acid shows potent cytotoxicity against MCF-7 cell line.|
|Revista Brasileira de Farmacognosia.2014 Oct;24(5):561–564. |
|Cytotoxic tirucallane triterpenes from the stem of Luvunga scandens.[Reference: WebLink]|
METHODS AND RESULTS:
Two tirucallane triterpenes, namely flindissol (1) and 3-Oxotirucalla-7,24-dien-21-oic acid (2), were isolated from the dichloromethane extract of the stem of Luvunga scandens (Roxb.) Buch-Ham ex Wight & Arn, Rutaceae. This is the first report of their isolation from this plant. Their structures were constructed by high resolution mass and 2D NMR spectroscopic data. The cytotoxic potential of the two pure compounds 1 and 3-Oxotirucalla-7,24-dien-21-oic acid were determined by MTT assay against human breast adenocarcinoma cell line (MCF-7).
Compounds 1 and 3-Oxotirucalla-7,24-dien-21-oic acid showed potent cytotoxicity against MCF-7 cell line with IC50 values of 13.8 μM and 27.5 μM, respectively. This result suggested their potential activity as antitumor agents.
3-Oxotirucalla-7,24-dien-21-oic acid Description
||The leaves of Rubus alceaefolius
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Zhong Yao Cai. 2015 Jan;38(1):93-6. |
|Study on Chemical Constituents of Petroleum Ether Fraction from Rubus alceaefolius.[Pubmed: 26214876]|
|To investigate the chemical constituents of Rubus alceaefolius.
METHODS AND RESULTS:
Nine compounds were isolated and purified from the petroleum ether extract of 95% alcohol extract of Rubus alceaefolius by repeated column chromatography on silica, Sephadex LH-20 and structurally identified by spectral analysis.
The compounds were identified as chrysophanol(1), physcion (2), β-sitosterol(3), 3-oxotirucalla-7, 24-dien-21-oic acid(4), myricadiol(5), 19-α-hydroxy-3-acetyl-ursolic acid(6), N-benzoylphenylalaninyl-N-benzoylphenylalaninate(7), aurantiamide acetate(8) and euscaphic acid(9).
Compounds land 4~8 are isolated from this plant for the first time, and compounds 4 - 8 are found in plants of Rubus genus for the first time.