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5,7-dimethoxy-2,2-dimethylchromene
5,7-dimethoxy-2,2-dimethylchromene
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 5,7-dimethoxy-2,2-dimethylchromene
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CAS No.: 21421-66-9
Catalog No.: CFN91941
Molecular Formula: C13H16O3
Molecular Weight: 220.26 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The herbs of Centaurea solstitialis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
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Biological Activity
Description: 5,7-Dimethoxy-2,2-dimethylchromene is a potential inhibitor of juvenile hormone onLocusta migratoria.
In vitro:
Experientia,1980,36(4):379-380.
Activity of precocene analogs onLocusta migratoria migratorioides (R. and F.)[Reference: WebLink]

METHODS AND RESULTS:
Several analogs of precocene have been synthesized and evaluated as potential inhibitors of juvenile hormone on Locusta migratoria.
CONCLUSIONS:
Only 5,7-dimethoxy-2,2-dimethylchromene was active; its ED50 and LD50 were measured and compared to those of precocene I and II.
5,7-dimethoxy-2,2-dimethylchromene Description
Source: The herbs of Centaurea solstitialis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.5401 mL 22.7004 mL 45.4009 mL 90.8018 mL 113.5022 mL
5 mM 0.908 mL 4.5401 mL 9.0802 mL 18.1604 mL 22.7004 mL
10 mM 0.454 mL 2.27 mL 4.5401 mL 9.0802 mL 11.3502 mL
50 mM 0.0908 mL 0.454 mL 0.908 mL 1.816 mL 2.27 mL
100 mM 0.0454 mL 0.227 mL 0.454 mL 0.908 mL 1.135 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN97708Precocene II644-06-4220.27C13H16O3
CFN919415,7-dimethoxy-2,2-dimethylchromene21421-66-9220.26C13H16O3
CFN99880Demethoxyencecalin19013-07-1202.3 C13H14O2
CFN91706Demethylisoencecalin24672-84-2218.3C13H14O3
CFN97155De-O-methylacetovanillochromene67667-62-3218.3 C13H14O3
CFN99879Eupatoriochromene19013-03-7218.3 C13H14O3
CFN98036Encecalin20628-09-5232.3 C14H16O3
CFN89538Ageratochromene dimer17678-76-1440.52C26H32O6
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