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    5-Epicanadensene
    5-Epicanadensene
    Information
    CAS No. 220384-17-8 Price
    Catalog No.CFN89051Purity>=98%
    Molecular Weight594.65Type of CompoundDiterpenoids
    FormulaC30H42O12Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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  • Biological Activity
    Description: 5-Epicanadensene is a natural product from Taxus sumatrana.
    In vitro:
    Biological Sciences, 2007.
    Studies on Diterpenoid Constituents from Taxus sumatrana in Taiwan.[Reference: WebLink]
    Taxol is a complex polyoxygenated diterpene isolated from Pacific yew (Taxus brevifolia). The structures of Taxoids are diversified with species, season and growth environment and the clinical effectiveness of Taxol as a microtubule-stabilizing therapeutic agent for treatment of several malignancies has motivated many scientists to isolate new taxoids and investigate their anti-tumor activities.
    METHODS AND RESULTS:
    In this continuing search for new and bioactive natural taxoids, reinvestigation of the acetone extract of the twigs, needles and branches of Taxus sumatrana (Taxaceae) afforded thirty-seven taxane diterpenes esters, including sumataxins sumataxin A (1)¡Bsumataxin B (2)¡Bsumataxin C (3)¡Bsumataxin D (4)¡Btaxuyunnanine C (5)¡B5a,7B,9a,10B,13a-petaacetoxy-4(20),11-taxadiene (6)¡B2a,5a,9a,10B,14B-pentaacetoxytaxa-4(20),11-taxadiene (7)¡B14B-hydroxytaxusin (8)¡B2a-deacetoxytaxinine J (9)¡Btaxa-4-(20),11-diene-2a,5a,7B,9a,10B,13a-hexaol hexaacetate (10)¡B1-dehydroxy baccatin VI (11)¡B7B,9a,10B,13a,20-pentaacetoxy-2a-benzoyloxy-4a,5a-dihydroxytax-11-ene (12)¡Btaxacin (13)¡Bbaccatin VI (14)¡Btaxuspinanane J (15)¡B2-deacetoxy-5-decinnamoyltaxinine J (16)¡BN-Methyl taxol C (17)¡B10-deacetyl yunnanaxane (18)¡Btaxumairol B (19)¡Btaxinine M (20)¡Bbaccatin III (21)¡Btaxuspinanane I (22)¡Btaxumairol K (23)¡Bwallifoliol (24)¡B13-oxo-baccatin III (25)¡Btaxol (26)¡B7-epi-10-deacetyl taxol (27)¡B10-deacetyl-13-oxo-baccatin III (28)¡B19-hydroxybaccatin III (29)¡B10-deacetyl taxol (30)¡B10-deacetyl-baccatin III (31)¡B13-acetyl-13-decinamoyltaxachinin B (32)¡B5-deacetyltaxachitriene B (33)¡B5-Epicanadensene (34)¡Btaxezopidine F (35)¡B13a,7B-diacetoxy-2a,5a,10B-trihydroxy-9-keto-2(3¡÷20)abeotaxane (36)¡B2-deacetyl taxine B (37). The structures of new compounds were established on the basis of their spectroscopic analyses.
    CONCLUSIONS:
    Among them, compounds 1, 2, 3 and 4 are new compounds from natural source, 2a-deacetoxytaxinine J (9)¡Btaxuspinanane J (15) had effects on PBMC (Peripheral Blood Mononuclear Cells) proliferation, and sumataxin A¡BD (1¡B4) had light exhibitedactivity of HSV-1.
    5-Epicanadensene Description
    Source: The branches of Taxus sumatrana.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.6817 mL 8.4083 mL 16.8166 mL 33.6332 mL 42.0415 mL
    5 mM 0.3363 mL 1.6817 mL 3.3633 mL 6.7266 mL 8.4083 mL
    10 mM 0.1682 mL 0.8408 mL 1.6817 mL 3.3633 mL 4.2042 mL
    50 mM 0.0336 mL 0.1682 mL 0.3363 mL 0.6727 mL 0.8408 mL
    100 mM 0.0168 mL 0.0841 mL 0.1682 mL 0.3363 mL 0.4204 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.