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    6-Acetonyl-N-methyl-dihydrodecarine
    Information
    CAS No. 1253740-09-8 Price
    Catalog No.CFN99367Purity>=98%
    Molecular Weight391.4 Type of CompoundAlkaloids
    FormulaC23H21NO5Physical DescriptionYellow powder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    Biological Activity
    Description: 1. 6-Acetonyl- N -methyl-dihydrodecarine has mosquito larvicidal activity against the malaria vector Anopheles gambiae.
    Targets: Antifection
    6-Acetonyl-N-methyl-dihydrodecarine Description
    Source: The fruits of Evodia rutaecarpa
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
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    doi: 10.3390/molecules22111829.

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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.5549 mL 12.7747 mL 25.5493 mL 51.0986 mL 63.8733 mL
    5 mM 0.511 mL 2.5549 mL 5.1099 mL 10.2197 mL 12.7747 mL
    10 mM 0.2555 mL 1.2775 mL 2.5549 mL 5.1099 mL 6.3873 mL
    50 mM 0.0511 mL 0.2555 mL 0.511 mL 1.022 mL 1.2775 mL
    100 mM 0.0255 mL 0.1277 mL 0.2555 mL 0.511 mL 0.6387 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    6-Acetonyl-N-methyl-dihydrodecarine References Information
    Citation [1]

    Journal of the Brazilian Chemical Society (Impact Factor: 1.25). 01/2009; 20(2).

    Fernandes CC et al. 6-acetonyl-N-methyl-dihydrodecarine, a new alkaloid from Zanthoxylum riedelianum. J. Braz. Chem. Soc 20: 379-382[Reference: WebLink]
    A new benzophenanthridine alkaloid, 6-Acetonyl-N-methyl-dihydrodecarine was isolated from Zanthoxylum riedelianum roots together with lupeol, 6-acetonyldihydrochelerythrine and 6-acetonyldihydroavicine. The structures were established from the IR, MS and NMR spectral data, including 2D-NMR experiments.
    Citation [2]

    Pesticide Biochem. Physiol., 2011, 99(1):82-5.

    Mosquito larvicidal activity of alkaloids from Zanthoxylum lemairei against the malaria vector Anopheles gambiae[Reference: WebLink]
    Four alkaloids, 10-O-demethyl-17-O-methylisoarnottianamide 1, 6-Acetonyl-N-methyl-dihydrodecarine 2, nitidine 3, and chelerythrine 4 were isolated from the plant Zanthoxylum lemairei (Rutaceae) and evaluated for mosquito larvicidal activity against the malaria vector Anopheles gambiae. The mortalities of the larvae were determined after 24 h. The results of the larvicidal tests demonstrated that compounds 1 and 2 were the most potent with mortality rates of 96.7% and 98.3% at a concentration of 250 mg/L, respectively. Compound 3 was less potent with a mortality of 28.3% at the same concentration. The percent mortality of 100% was observed at a concentration of 500 mg/L. The least potent of the four alkaloids was compound 4, which achieved 100% mortality at 1000 mg/L. These findings could be useful in the research for newer more selective, biodegradable and natural larvicidal compounds or can be used as lead compounds for the development of larvicides.