ChemFaces is a professional high-purity natural products manufacturer.
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2. Pharmacological research
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More articles cited ChemFaces products.
Sci Rep. 2017 Jan 9;Inflammation. 2015 Feb 6.Korean Society of Pharm. Sci.2017;J Bone Miner Res. 2017 Jul 26.BMC Complement Altern Med.2014 Jul 14;14:242.
Sci Rep. Jan. 2018Separation Science and Technology2016 Mar,23Phytochem Anal.2016 Sep;J Ethnopharmacol. 2017 Feb 23;Journal of Functional FoodsMarch 2017
Fitoterapia.2015 Jan;100:179-86.Gorana Nedin Rankovi?2017 Jan 15Journal of Life Science2017.2;Biochem Biophys Res Commun.2017 Jan 22;
Our products had been exported to the following research institutions and universities, And still growing.
Utah State University (USA)Uniwersytet Jagielloński w Krak... (Poland)Anna University (India)MTT Agrifood Research Finland (Finland)
University of Toronto (Canada)Leibniz-Institut für Pflanzenbi... (Germany)Universidad Miguel Hernández (Spain)University of Canterbury (New Zealand)
Cornell University (USA)Helmholtz Zentrum München (Germany)Washington State University (USA)
|| 6alpha-Hydroxypolyporenic acid C is a natural product from Wolfiporia cocos (Schw.) Ryv.|
|Zhongguo Zhong Yao Za Zhi. 2008 Jul;33(13):1596-601. |
|Absorption of triterpenoid compounds from Indian bread (Poria cocos) across human intestinal epithelial (Caco-2) cells in vitro.[Pubmed: 18837324]|
|To study the absorption of 3-epidehydrotumulosic acid (EDHTA), polyporenic acid C (PPAC) and 6alpha-Hydroxypolyporenic acid C (HPPA) isolated from the sclerotium of Poria cocos. In human intestinal epithelial. |
METHODS AND RESULTS:
By using Caco-2 (the human colonic adenocarcinoma cell lines) cells monolayer as an intestinal epithelial cell model, the permeability of EDHTA, PPAC and 6alpha-Hydroxypolyporenic acid C were studied from apical side (AP side) to basolateral side (BL side) or from BL side to AP side.The P(app) values of EDHTA and PPAC were at a nearly same magnitude with those of propranolol, and 6alpha-Hydroxypolyporenic acid C lied between those of propranolol and atenolol. On the other hand, the efflux transport of EDHTA, PPAC and 6alpha-Hydroxypolyporenic acid C were higher 1.78, 1.91 and 2. 47 times more than its influx transport with 0.56, 0.52 and 0.41 rate of P(app A --> B)/P(app (B --> A).
EDHTA, PPAC and 6alpha-Hydroxypolyporenic acid C can be absorbed across intestinal epithelial cells, among EDHTA and PPAC will be completely. 6alpha-Hydroxypolyporenic acid C will be moderately absorbed compounds. EDHTA, PPAC and 6alpha-Hydroxypolyporenic acid C may have been involved in efflux mechanism in Caco-2 cells monolayers model from the basolateral-to-apical direction.
6alpha-Hydroxypolyporenic acid C Description
||The roots of Wolfiporia cocos (Schw.) Ryv.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.