ChemFaces is a professional high-purity natural products manufacturer.
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $322.6 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Int J Mol Sci.2015, 16(8):18396-411J Breast Cancer.2015, 18(2):112-118Food Science and Biotechnology...2015...Korean J. of Food Sci. and Tech...2016...J Pharm Anal.2016, 6(6):363-373Evid Based Complement Alternat Me...2017...Molecules.2017, 22(3)Front Immunol.2017, 8:1542
Nutrients.2018, 11(1):E17BMC Complement Altern Med....2018...Evid Based Complement Alternat Me...2018...Sci Rep.2018, 8:15059J Nat Prod.2018, 81(4):966-975Phytother Res.2019, 10.1002Front Microbiol.2019, 10:2806Int J Mol Sci.2019, 20(3):E651
Molecules.2019, 24(24):E4536Exp Biol Med (Maywood)....2019...Chin J Pharm Anal.2019, 39(7):1217-1228Phytomedicine.2019, 59:152785Phytomedicine.2019, 61:152813Appl. Sci.2020, 10,1304Biochem Biophys Res Commun....2020...
Our products had been exported to the following research institutions and universities, And still growing.
Pennsylvania State University (USA)Cancer Research Initatives Foun... (Malaysia)Molecular Biology Institute of ... (Spain)Wageningen University (Netherlands)
Uniwersytet Medyczny w ?odzi (Poland)St. Jude Children Research Hosp... (USA)Worcester Polytechnic Institute (USA)University of Bordeaux (France)
Washington State University (USA)Monash University Sunway Campus (Malaysia)Universiti Sains Malaysia (Malaysia)
Related Screening Libraries
||7-O-Methylaloeresin A shows significant antioxidant activity, it also has moderate inhibitory active on BACE. 7-O-Methylaloeresin A exhibits good activity against multiple drug resistant Staphylococcus aureus (NCTC 11994) and Salmonella typhimurium (ATCC 1255) with MIC values of 0.72 and 0.18 mm, respectively. |
|Phytother Res. 2011 Dec;25(12):1756-60. |
|In vitro antimicrobial and antioxidant activities of anthrone and chromone from the latex of Aloe harlana Reynolds.[Pubmed: 21452374]|
|Anthrone (aloin) and chromone (7-O-Methylaloeresin A).
METHODS AND RESULTS:
The latex and its two constituents were assessed for their possible antimicrobial activities against 23 bacterial and four fungal strains using the disc diffusion method and their antioxidant activity by two complementary test systems, namely 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2-deoxyribose degradation assay methods. The isolated compounds showed promising results against various pathogenic bacterial and fungal strains in comparison with standard drugs. Moreover, 7-O-Methylaloeresin A exhibited good activity against multiple drug resistant Staphylococcus aureus (NCTC 11994) and Salmonella typhimurium (ATCC 1255) with MIC values of 0.72 and 0.18 mm, respectively. Among the fungal strains tested, Candida albicans (ATCC 10231) was the most susceptible organism to the latex and the two isolated compounds. The latex and isolated compounds also showed significant activities on both antioxidant assays with the highest activity being observed for 7-O-Methylaloeresin A, which gave IC(50) values of 0.026 mm and 0.021 mm for DPPH and 2-deoxyribose degradation assay, respectively.
These findings support the traditional uses of the plant for the treatment of various infectious and inflammatory diseases.
7-O-Methylaloeresin A Description
||The herbs of Aloe arborescens Mill.
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Yao Xue Xue Bao. 2006 Oct;41(10):1000-3. |
|Active constituents from Aloe arborescens as BACE inhibitors.[Pubmed: 17184120]|
|To seek for new components as BACE inhibitors from Aloe arborescens.
METHODS AND RESULTS:
The chemical constituents were isolated by chromatographic methods and their structures were elucidated on the basis of spectral analysis.
Eight compounds were isolated and their structures identified as 6'-O-isobutyryl aloenin A (1), aloenin A (2), aloe-emodin (3), (E)-2-acetonyl-8-(2'-O-feruloxyl)-beta-D-glucopyranosyl-7-methoxy-5-methyl-chromone (4), 7-O-Methylaloeresin A (5), babarloin A (6), elgonica-dimer A (7), and elgonica-dimer B (8), separately.
Compound 1 is a new compound, and compound 4 was isolated from A. arborescens for the first time. Pharmacological tests indicated that 2, 4, 5 and 6 have moderate inhibitory active on BACE.