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    8-O-Methylretusin-7-O-beta-D-glucopyranoside
    8-O-Methylretusin-7-O-beta-D-glucopyranoside
    Information
    CAS No. 68862-13-5 Price
    Catalog No.CFN92917Purity>=98%
    Molecular Weight460.43Type of CompoundFlavonoids
    FormulaC23H24O10Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Flavonoids Compound Library
  • Antifection Inhibitor Library
  • Biological Activity
    Description: 8-O-Methylretusin-7-O-beta-D-glucopyranoside shows significant antimicrobial activity with a broad spectrum as well as antioxidant activity.
    Targets: Antifection
    In vitro:
    Int J Mol Sci. 2012;13(9):11349-64.
    Phenolic compounds from Halimodendron halodendron (Pall.) voss and their antimicrobial and antioxidant activities.[Pubmed: 23109858 ]
    Halimodendron halodendron has been used as forage in northwestern China for a long time. Its young leaves and flowers are edible and favored by indigenous people.
    METHODS AND RESULTS:
    In this study, eleven phenolic compounds were bioassay-guided and isolated from the aerial parts of H. halodendron for the first time. They were identified by means of physicochemical and spectrometric analysis as quercetin (1), 3,5,7,8,4'-pentahydroxy-3'-methoxy flavone (2), 3-O-methylquercetin (3), 3,3'-di-O-methylquercetin (4), 3,3'-di-O-methylquercetin-7-O-β-d-glucopyranoside (5), isorhamentin-3-O-β-d-rutinoside (6), 8-O-methylretusin (7), 8-O-Methylretusin-7-O-beta-D-glucopyranoside (8), salicylic acid (9), p-hydroxybenzoic acid (ferulic acid) (10), and 4-hydroxy-3-methoxy cinnamic acid (11). They were sorted as flavonols (1-6), soflavones (7 and 8), and phenolic acids (9-11). Among the compounds, flanools 1-4 revealed a strong antibacterial activity with minimum inhibitory concentration (MIC) values of 50-150 μg/mL, and median inhibitory concentration (IC(50)) values of 26.8-125.1 μg/mL. The two isoflavones (7 and 8) showed moderate inhibitory activity on the test bacteria. Three phenolic acids (9, 10 and 11) showed strong antibacterial activity with IC(50) values of 28.1-149.7 μg/mL. Antifungal activities of the compounds were similar to their antibacterial activities. All these phenolic compounds showed significant antimicrobial activity with a broad spectrum as well as antioxidant activity based on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and β-carotene-linoleic acid bleaching assays. In general, the flavonol aglycones with relatively low polarity exhibited stronger activities than the glycosides.
    CONCLUSIONS:
    The results suggest the potential of this plant as a source of functional food ingredients and provide support data for its utilization as forage as well.
    8-O-Methylretusin-7-O-beta-D-glucopyranoside Description
    Source: The herbs of Cladrastis platycarpa
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1719 mL 10.8594 mL 21.7188 mL 43.4377 mL 54.2971 mL
    5 mM 0.4344 mL 2.1719 mL 4.3438 mL 8.6875 mL 10.8594 mL
    10 mM 0.2172 mL 1.0859 mL 2.1719 mL 4.3438 mL 5.4297 mL
    50 mM 0.0434 mL 0.2172 mL 0.4344 mL 0.8688 mL 1.0859 mL
    100 mM 0.0217 mL 0.1086 mL 0.2172 mL 0.4344 mL 0.543 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.