|Description:||1. 9-Deoxygoniopypyrone shows significant cytotoxicity against human tumor cells.|
|Source:||The herbs of Goniothalamus yunnanensis|
|Solvent:||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||4.268 mL||21.3402 mL||42.6803 mL||85.3606 mL||106.7008 mL|
|5 mM||0.8536 mL||4.268 mL||8.5361 mL||17.0721 mL||21.3402 mL|
|10 mM||0.4268 mL||2.134 mL||4.268 mL||8.5361 mL||10.6701 mL|
|50 mM||0.0854 mL||0.4268 mL||0.8536 mL||1.7072 mL||2.134 mL|
|100 mM||0.0427 mL||0.2134 mL||0.4268 mL||0.8536 mL||1.067 mL|
Molecules. 2012 Dec 21;18(1):128-39.
|Cytotoxic and antioxidant compounds from the stem bark of Goniothalamus tapisoides Mat Salleh.[Pubmed: 23344192]|
|Eleven compounds:goniomicin A (1), goniomicin B (2), goniomicin C (3), goniomicin D (4), tapisoidin (5), goniothalamin (6), 9-Deoxygoniopypyrone (7), pterodondiol (8), liriodenine (9), benzamide (10) and cinnamic acid (11), were isolated from the stem bark of Goniothalamus tapisoides. All compounds were identified by spectroscopic analysis and, for known compounds, by comparison with published data. Goniothalamin (6) exhibited mild cytotoxic activity towards a colon cancer cell line (HT-29), with an IC(50)value of 64.17 ± 5.60 µM. Goniomicin B (2) give the highest antioxidant activity in the DPPH assay among all compounds tested, with an IC(50) of 0.207 µM.|
J Nat Prod. 1991 Jul-Aug;54(4):1034-43.
|Two new styryl lactones, 9-deoxygoniopypyrone and 7-epi-goniofufurone, from Goniothalamus giganteus.[Pubmed: 1791471]|
|Two new styryl lactones, 9-Deoxygoniopypyrone  and 7-epi-goniofufurone , and a known styryl lactone, goniodiol , were isolated from the stem bark of Goniothalamus giganteus. The structures were elucidated by ir, ms, 1H-nmr, 13C-nmr, and 1H-1H COSY spectra; the relative configurations were determined by X-ray crystallographic analysis. Unlike goniopypyrone  and goniofufurone , neither of the new styryl lactones 9-Deoxygoniopypyrone and 3 showed significant bioactivities to human tumor cells. However, goniodiol  showed significant and selective cytotoxicity against human lung tumor cells (A-549).|