ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
Am J Chin Med.2016;44(8)J Ethnopharmacol. 2017 Feb 23;J. Soc. Cosmet. Sci. KoreaJune 2016Food Research InternationalApr. 2018;J Nat Prod. 2017 Apr 28;
J Agric Food Chem.2016 Sep 7PhytomedicineFeb. 11. 2016Acta ChromatographicaOct. 11, 2016Molecules. 2017 Feb 8;US20170000760 A1Jan 5, 2017
Phytomedicine1 Feb. 2018;LWT - Food Science and Technology2017 Jan.Korean Herb. Med. Inf. 2016;4(1):35-42Integr Med Res.2017 Dec;
Our products had been exported to the following research institutions and universities, And still growing.
Donald Danforth Plant Science Ce... (USA)University of Medicine and Pharm... (Romania)Chinese University of Hong Kong (China)Aveiro University (Portugal)
University of Indonesia (Indonesia)Sanford Burnham Prebys Medical D... (USA)Complutense University of Madrid (Spain)National Hellenic Research Found... (Greece)
Heinrich-Heine-University Düsse... (Germany)Universite de Lille1 (France)Northeast Normal University Chan... (China)
|| Acetoxyisovalerylalkannin may have anti-ageing activity, it can upregulate Collagen-I, elastin and involucrin syntheses in human dermal fibroblasts or keratinocytes. |
|Natural Product Research, 2015, Mar 26,30(5):574-577. |
|Anti-skin ageing activity of napthoquinones from Arnebia nobilis Reichb.f.[Pubmed: 25810219]|
|The present isolation and identification of napthoquinones from roots of Arnebia nobilis Reichb.f. can lead to the discovery of new anti-skin ageing ingredient in colour cosmetics.
METHODS AND RESULTS:
Four compounds have been isolated and purified by rigorous column chromatography. The compounds are identified as β, β-dimethylacryl alkannin (AN-I), Acetoxyisovalerylalkannin (AAN-II), acetyl alkannin (AN-III) and alkannin (AN-IV) by interpretation of spectroscopic data. This study is the first to report the isolation of Acetoxyisovaleryl alkannin (AAN-II) from A. nobilis. The IC50 values of the compounds, determined in human skin cells (human dermal fibroblasts and human keratinocytes) and mouse embryonic fibroblasts (NIH3T3) varied significantly among the four alkannins. Among the four compounds, β-acetoxyisovaleryl alkannin (AAN-II) significantly inhibited hydrogen peroxide (H2O2)-induced red blood corpuscle haemolysis and cellular senescence in human dermal fibroblasts. Collagen-I, elastin and involucrin syntheses in human dermal fibroblasts or keratinocytes were up regulated by AAN-II.
These results support the potential utility of alkannins as novel anti-ageing ingredients.
||The roots of Lithosperraum erythrorhizon Sieb. et Zucc.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Journal of Jilin University, 2010 , 48 (2) :319-322. |
|Chemical Constituents from Root of Arnebia euchroma(Royle)Johnst[Reference: WebLink]|
|All the compounds were separated from the petroleum ether extracts of Arnebia euchroma root by means of column chromatography and their structures were identified by the spectral analysis and chemical evidence.
METHODS AND RESULTS:
Seven compounds were separated and identified as deoxyshikonin (1),β,β-dimethylacryloylshikonin (2),acetyshikonin (3),shikonin (4),β-sitosterol (5),propionylshikonin (6),Acetoxyisovalerylalkannin (7).