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    CAS No. 93-29-8 Price $30 / 20mg
    Catalog No.CFN96771Purity>=98%
    Molecular Weight206.24Type of CompoundPhenylpropanoids
    FormulaC12H14O3Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Our products had been exported to the following research institutions and universities, And still growing.
  • Universitas islam negeri Jakarta (Indonesia)
  • Uniwersytet Gdański (Poland)
  • Technical University of Denmark (Denmark)
  • Agricultural Research Organizati... (Israel)
  • Sri Ramachandra University (India)
  • Universidad Industrial de Santan... (Colombia)
  • University of Bordeaux (France)
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  • Korea Food Research Institute(KF... (Korea)
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    Ganoderic acid S

    Catalog No: CFN99066
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    Biological Activity
    Description: Acetylisoeugenol is a mild sensitizer in vivo, it shows good antifungal activities against R. solani and F. oxysporum.
    Targets: Antifection
    In vitro:
    Industrial Crops & Products, 2017, 97:388-394.
    Structure-activity relationships of cinnamaldehyde and eugenol derivatives against plant pathogenic fungi.[Reference: WebLink]

    Cinnamon bark oil showed a lower activity than clove bud oil. The fungicidal activity of cinnamaldehyde (IC50 = 75.4 and 156.9 μg/mL, respectively) and eugenol (IC50 = 58.9 and 52.9 μg/mL, respectively) against R. solani and F. oxysporum was also evalutated. Comparisons of the antifungal activities of cinnamaldehyde and eugenol derivatives revealed that α-methylcinnamaldehyde, α-methylcinnamic acid, methyleugenol, acetyleugenol, isoeugenol, methylisoeugenol, and Acetylisoeugenol showed good antifungal activities against R. solani and F. oxysporum. In structure-activity relationships, the fungicidal activity of cinnamaldehyde derivatives could be related to conjugated double bond and the length of CH chain outside the ring. In addition, the presence of the lipophilicity may have a considerable influence on the toxicity of phenylpropenes.
    The present approach may help future work in the search for fungicidal compounds.
    In vivo:
    J Dermatol. 1985 Apr;12(2):153-60.
    Factors influencing conjugation of phenolic compounds with the epsilon-amino group.[Reference: WebLink]

    Factors influencing the conjugation potency of eugenol (E), isoeugenol (IE), methyl isoeugenol (MIE), and Acetylisoeugenol (AIE) with [l-14C]07-aminocaproic acid are investigated. The conjugation reaction for IE is accelerated in the presence of H2O2-peroxidase and inhibited under anaerobic conditions by nitrogen gas flow. An oxidation reaction is found to be necessary for the conjugation of IE with 07-aminocaproic acid. Immediately after mixing the phenolic compounds with [1-14C]07-aminocaproic acid and H2O2-peroxidase, the main conjugates are 7.7% for IE, 2.1% for E, 0.7% for AIE, and 0.2% for MIE. IE, which is a potent sensitizer in vivo, produces the greatest amount of conjugates while MIE, which is negative in vivo, produces almost no conjugates.
    AIE and E, both mild sensitizers in vivo, produce less conjugates than IE.
    Acetylisoeugenol Description
    Source: From Cinnamon bark oil.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
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    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.8487 mL 24.2436 mL 48.4872 mL 96.9744 mL 121.218 mL
    5 mM 0.9697 mL 4.8487 mL 9.6974 mL 19.3949 mL 24.2436 mL
    10 mM 0.4849 mL 2.4244 mL 4.8487 mL 9.6974 mL 12.1218 mL
    50 mM 0.097 mL 0.4849 mL 0.9697 mL 1.9395 mL 2.4244 mL
    100 mM 0.0485 mL 0.2424 mL 0.4849 mL 0.9697 mL 1.2122 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.