ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
Microchemical JournalMarch 2018;Phytomedicine15 Dec. 2015,1262–1268The Korea Society of Pharmacognosy.2014Polytechnic University of Catalonia2016Korean J. of Horticultural Sci. & Tech. No.2, 2017.2
Chemistr of plant2016021195Sci Rep. 2017 Dec 11;Arch Biochem Biophys. 2018 Jan 15;International Journal of Pharmacognosy.2015 7(1).Advance Publication2015 Aug 18
Molecules. 2017 Mar 7;US20170000760 A1Jan 5, 2017Phytochem Anal.2013 Sep-Oct.Horticultural Science2016
Our products had been exported to the following research institutions and universities, And still growing.
The Ohio State University (USA)Chinese University of Hong Kong (China)Heinrich-Heine-University Düsse... (Germany)Fraunhofer-Institut für Molekul... (Germany)
University of Hawaii Cancer Center (USA)Griffith University (Australia)Sri Sai Aditya Institute of Phar... (India)Universidade Federal de Pernambu... (Brazil)
University of Canterbury (New Zealand)Max Rubner-Institut (MRI) (Germany)Universite Libre de Bruxelles (Belgium)
||Alisol C can improve glucose uptake in Hep G2 cells, it may be one of the therapeutic material basis in hypoglycemic activities in A. orientalis. Alisol C,16,23-oxido-alisol B and alisol O in Zexie may cause nephrotoxicity.|
|Chinese Traditional & Herbal Drugs, 2014, 45(22):3238-45. |
|Chemical constituents from Alisma orientalis extracts with hypoglycemic effect[Reference: WebLink]|
|To study the chemical constituents in Alisma orientalis extracts with hypoglycemic effect. |
METHODS AND RESULTS:
To study the in vivo hypoglycemic effects of A. orientalis extracts, high fat diet (HFD)-induced insulin resistance male C57BL/6J mice were treated with water and ethanol extracts of A. orientalis in diet, and glucose tolerance test was carried out following the intervention. Silica gel, ODS, and preparative HPLC were used to isolate the compounds. Their chemical structures were elucidated on the basis of NMR and MS spectral data. Sixteen compounds were identified as sitosterol (1), palmitic acid (2), heptadecanoic acid (3), eicosanoic acid (4), 11-deoxy-alisol B (5), 23-acetate alisol B (6), 23-acetate Alisol C (7), alisol B (8), 24-acetate alisol A (9), alisol G (10), 24-acetate alisol F (11), alisol L (12), Alisol C (13), alisol F (14), alisol A (15), and 16-oxo-24-acetate alisol A (16), and nine of the triterpenes could improve glucose uptake in HepG2 cells.
Compounds 3 and 4 are isolated from A. orientalis for the first time. The water and ethanol extracts of A. orientalis could improve glucose tolerance test. Triterpenes may be one of the therapeutic material basis in hypoglycemic activities in A. orientalis.
Alisol C Description
||The tubers of Alisma plantago-aquatica Linn.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.