• ChemFaces is a professional high-purity natural products manufacturer.
  • Product Intended Use
  • 1. Reference standards
  • 2. Pharmacological research
  • 3. Inhibitors
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • Natural Products
    Betaine hydrochloride
    Information
    CAS No. 590-46-5 Price $30 / 20mg
    Catalog No.CFN99547Purity>=98%
    Molecular Weight153.60Type of CompoundAlkaloids
    FormulaC5H12ClNO2Physical DescriptionWhite cryst.
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
    Citing Use of our Products
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $7.0 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
  • Monash University (Australia)
  • University of Hull (United Kingdom)
  • Medical University of Gdansk (Poland)
  • University of Wollongong (Australia)
  • Sanford Burnham Prebys Medical ... (USA)
  • University of Wuerzburg (Germany)
  • Korea Food Research Institute(K... (Korea)
  • Monash University Malaysia (Malaysia)
  • Kamphaengphet Rajabhat University (Thailand)
  • Molecular Biology Institute of ... (Spain)
  • University of Helsinki (Finland)
  • More...
  • Package
    Featured Products
    Shikonin

    Catalog No: CFN99907
    CAS No: 517-88-4
    Price: $80/20mg
    Chrysin 6-C-arabinoside 8-C-glucos...

    Catalog No: CFN92284
    CAS No: 185145-33-9
    Price: $368/5mg
    Ginsenoside Rk3

    Catalog No: CFN92593
    CAS No: 364779-15-7
    Price: $180/10mg
    Perillen

    Catalog No: CFN90862
    CAS No: 539-52-6
    Price: $168/20mg
    Ginsenoside Rh3

    Catalog No: CFN99972
    CAS No: 105558-26-7
    Price: $218/20mg
    Mulberroside A

    Catalog No: CFN99586
    CAS No: 102841-42-9
    Price: $100/20mg
    Terrestrosin K

    Catalog No: CFN90822
    CAS No: 193605-07-1
    Price: $218/10mg
    Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Hepatoprotective Compound Library
  • Analgesia Compound Library
  • Growth-promoting effects Compound Library
  • Thyroid stimulating effect Compound Library
  • Insulin-stimulated action Compound Library
  • Sedative hypnotics Compound Library
  • Antipyretic Compound Library
  • Anti-hypoxic Compound Library
  • Alkaloids Compound Library
  • Histone Methyltransferase Inhibitor Library
  • Biological Activity
    Description: Betaine hydrochloride is a natural compound found in many foods and also an active methyl-donor which can maintain normal DNA methylation patterns, which has anti-hypoxic, hepatoprotective, sedative, antipyretic and analgesic effects. Betaine hydrochloride can increase the secreting of thyroxine (T3) and insulin and regulate the metabolism of organism by the hormones, thus it prompts fish growth and also improves intestine figuration.
    Targets: Histone Methyltransferase
    In vivo:
    Journal of Fisheries of China, 2003, 27(6):564-9.
    Growth-promoting mechanism by betaine hydrochloride in Colossoma brachypomum.[Reference: WebLink]
    This research was conducted to approach growth-promoting mechanism by Betaine hydrochloride in Colossoma brachypomum fingerlings with average initial weight 83.14±15. 36g during October to December, 1997.
    METHODS AND RESULTS:
    The fish was fed for 60d under the conditions of circulation, filtration and controled temperature. The results of rearing indicated that Betaine hydrochloride obviously enhanced fish growth, decreased food conversion rate and improved feed efficiency; physiologically, Betaine hydrochloride increased the levels of T3 and insulin, increased the albumin content; Betaine hydrochloride decreased the urine nitrogen (UN) concentration significantly. The figure of tissue slices showed that Betaine hydrochloride improved villas and microvilli length, density and the distribution uniformity of duodenum. Betaine hydrochloride had no bad effects on supermicro-structure of live cell.
    CONCLUSIONS:
    The results of this research implicated that Betaine hydrochloride increases the secreting of thyroxine (T3) and insulin and regulates the metabolism of organism by the hormones. Thus it prompts fish growth. It also improved intestine figuration.
    Vet Med Nauki. 1976;13(6):66-71.
    [Effect of betaine hydrochloride on broiler chickens when used alone or in combination with vitamin B12].[Pubmed: 1014365 ]

    METHODS AND RESULTS:
    The studies were carried out with 2287 broilers aged from 3 to 56 days, divided when one-day-old into four equal groups. The first group were fed the common ration and served as controls. The remaining three groups were experimental, the broilers of the second group being offered the basic common ration enriched with 0.2 per cent betaine. The third group were also given the ordinary ration, however, they received in the drinking water some 10 mug vitamin BUI per one kilogram feed each. The fourth group received both betaine and vitamin B12 at the rates indicated.
    CONCLUSIONS:
    Results showed that Betaine hydrochloride offered either alone or in combination with vitamin B12 contributes to increasing the liveweight gain of broilers in the course of the starter period, but its use in doses of 0.2 per cent in the finishing period is not effective.
    Betaine hydrochloride Description
    Source: The roots of Beta vulgaris.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Recent ChemFaces New Products and Compounds
    Glyasperin C

    Catalog No: CFN95065
    CAS No: 142474-53-1
    Price: $333/5mg
    Epimedin K

    Catalog No: CFN95019
    CAS No: 174286-13-6
    Price: $288/5mg
    8-Hydroxypinoresinol diglucoside

    Catalog No: CFN95083
    CAS No: 112747-99-6
    Price: $318/5mg
    Physalin G

    Catalog No: CFN95104
    CAS No: 76045-38-0
    Price: $388/5mg
    Ganoderic acid H

    Catalog No: CFN92056
    CAS No: 98665-19-1
    Price: $399/5mg
    Magnoloside A

    Catalog No: CFN99232
    CAS No: 113557-95-2
    Price: $318/5mg
    8-Gingerol

    Catalog No: CFN99131
    CAS No: 23513-08-8
    Price: $168/20mg
    Sibiricaxanthone B

    Catalog No: CFN90644
    CAS No: 241125-81-5
    Price: $238/20mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 6.5104 mL 32.5521 mL 65.1042 mL 130.2083 mL 162.7604 mL
    5 mM 1.3021 mL 6.5104 mL 13.0208 mL 26.0417 mL 32.5521 mL
    10 mM 0.651 mL 3.2552 mL 6.5104 mL 13.0208 mL 16.276 mL
    50 mM 0.1302 mL 0.651 mL 1.3021 mL 2.6042 mL 3.2552 mL
    100 mM 0.0651 mL 0.3255 mL 0.651 mL 1.3021 mL 1.6276 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Animal Research:
    Inpharma Weekly, 2001, 1311(1):10-10.
    Betaine hydrochloride shows promise for treatment of nonalcoholic steatohepatitis.[Reference: WebLink]
    Betaine hydrochloride shows promise for treatment of nonalcoholic steatohepatitisBetaine-hydrochloride, therapeutic useHepatitis, treatment...
    Acta Pharm. Sin., 1986, 21(1):61-4.
    The sedative, antipyretic and analgesic effects of betaine hydrochloride[Reference: WebLink]
    When Betaine hydrochloride was given orally 250~1000 mg/kg, the motor activity of mice was reduced 50~81%. The hypnotic effect of pentobarbital was markedly increased after oral administration of Betaine hydrochloride at the dosage of 500 mg/kg or 1000 mg/kg. Analgesic effect of betaine was demonstrated in mice by the hot plate method (55℃) and the acetic acid writhing test when given intraperitoneally at the dosage of 540 mg/kg or 900 mg/kg. The analgesic effect of betaine (500 mg/kg) was antagonized by prior administration of atropine (5 mg/kg). Betaine hydrochloride (500 mg/kg) given by gastric intubation was shown to have antipyretic effect in rabbits with ⅳ TAB vaccine fever, but not in normotheric rabbits.