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Cynaustine
Cynaustine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Cynaustine
Price:
CAS No.: 17958-39-3
Catalog No.: CFN00237
Molecular Formula: C15H25NO4
Molecular Weight: 283.37 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Cynoglossum amabile
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Biological Activity
Description: Cynaustine is a natural product from Cynoglossum amabile.
Cynaustine Description
Source: The herbs of Cynoglossum amabile
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.529 mL 17.6448 mL 35.2896 mL 70.5791 mL 88.2239 mL
5 mM 0.7058 mL 3.529 mL 7.0579 mL 14.1158 mL 17.6448 mL
10 mM 0.3529 mL 1.7645 mL 3.529 mL 7.0579 mL 8.8224 mL
50 mM 0.0706 mL 0.3529 mL 0.7058 mL 1.4116 mL 1.7645 mL
100 mM 0.0353 mL 0.1764 mL 0.3529 mL 0.7058 mL 0.8822 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Australian Journal of Chemistry, 1967 , 20 (11) :2499-503.
The alkaloids of Cynoglossum australe R.Br. and C. amabile Stapf & Drummond[Reference: WebLink]

METHODS AND RESULTS:
Two new pyrrolizidine alkaloids, cynaustraline and Cynaustine, have been isolated from Cynoglossum australe R,.Br., and echinatine and a third new alkaloid, amabiline, from C. amabile Stapf & Drummond. Cynaustraline, Cynaustine, and amabiline are, respectively, (+)- isoretronecanol, (+)-supinidine, and (-)-supinidine esters of viridifloric acid.
CONCLUSIONS:
This is the first isolation of an ester of a (+)- enantiomer of an allylic amino alcohol.
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Piplartine

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Dehydroglyasperin C

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Procyanidin B3

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Salidroside

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Sakakin

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