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    Dammaradienyl acetate
    Dammaradienyl acetate
    Information
    CAS No. 52914-31-5 Price
    Catalog No.CFN98874Purity> 95%
    Molecular Weight468.8 Type of CompoundTriterpenoids
    FormulaC32H52O2Physical DescriptionCryst.
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)
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    Dammaradienyl acetate Description
    Source: The roots of Inula helenium L.
    Biological Activity or Inhibitors:
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1331 mL 10.6655 mL 21.3311 mL 42.6621 mL 53.3276 mL
    5 mM 0.4266 mL 2.1331 mL 4.2662 mL 8.5324 mL 10.6655 mL
    10 mM 0.2133 mL 1.0666 mL 2.1331 mL 4.2662 mL 5.3328 mL
    50 mM 0.0427 mL 0.2133 mL 0.4266 mL 0.8532 mL 1.0666 mL
    100 mM 0.0213 mL 0.1067 mL 0.2133 mL 0.4266 mL 0.5333 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Dammaradienyl acetate References Information
    Citation [1]

    Zhongguo Zhong Yao Za Zhi. 2010 Feb;35(3):327-30.

    Triterpenes from Kalimeris indica.[Pubmed: 20422998]
    The constituents were isolated by various chromatographic techniques and their structures were elucidated by their physicochemical properties and the spectral data analysis. Eleven compounds were isolated and identified as Dammaradienyl acetate(1), friedelin(2), friedelinol(3), beta-amyrin(4), alpha-amyrin(5), lupenyl acetate(6), beta-sitosterol(7), alpha-spinasterol(8), alpha-spinasterone(9), stigmasterol(10), daucosterol(11).
    Citation [2]

    Chinese Pharmaceutical Journal,2010,45 (10) :727-32.

    Antitumor Triterpenes from Scorzonera mongolica Maxim[Reference: WebLink]
    To study the anti-tumor active constituents of Scorzonera mongolica Maxim..METHODS The chemical components were isolated by silica gel H,Sephadex LH-20 column chromatography and semi-preparative HPLC.Structures were elucidated on the basis of physicochemical properities and spectral data.The anti-tumor experiment in vitro,the MTT and SRB methods were used to screen constituents of S.mongolica Maxim..RESULTS 15 Triterpenes were isolated and identified as lupeol (1),betulin (2),betulinic acid (3),lupeo acetate (4),23Z-3β-acetoxyeupha-7,23-diene-25-ol (5),Dammaradienyl acetate (6),pulcherryl acetate (7),taraxasterol (8),taraxasteryl acetate (9),ψ-taraxasterol (10),ψ-taraxasteryl acetate (11),α-amyrin acetate (12),dammar-24-ene-3,20-diol,3β-tetradecanoate (13),butyrospermyl acetate (14) and multiflorenyl acetate (15),respectively.CONCLUSION Compound 1-15 were obtained from the plant for the first time and compound 2,3,5-15 were obtained from the genus Scorzonera for the first time.Compound 1-5 demonstrated significant inhibitory effects on A-549 cancer cells and compound 14 showed also strong cytotoxity against Bel-7402 cancer cells at the concentration of 50 mg·L-1.