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    Deacetylasperulosidic acid
    Information
    CAS No. 14259-55-3 Price $538 / 10mg
    Catalog No.CFN92358Purity>=98%
    Molecular Weight390.3Type of CompoundIridoids
    FormulaC16H22O11Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)
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    Deacetylasperulosidic acid Description
    Source: The herbs of Hedyotis diffusa Willd.
    Biological Activity or Inhibitors: 1. Deacetylasperulosidic acid may increase catalase activity.
    2. Deacetylasperulosidic acid inhibits the reduction of ear swelling, and also cancels the suppression of IL-2 production along with the activation of natural killer cells in the same manner as that of Noni-ext.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.5621 mL 12.8107 mL 25.6213 mL 51.2426 mL 64.0533 mL
    5 mM 0.5124 mL 2.5621 mL 5.1243 mL 10.2485 mL 12.8107 mL
    10 mM 0.2562 mL 1.2811 mL 2.5621 mL 5.1243 mL 6.4053 mL
    50 mM 0.0512 mL 0.2562 mL 0.5124 mL 1.0249 mL 1.2811 mL
    100 mM 0.0256 mL 0.1281 mL 0.2562 mL 0.5124 mL 0.6405 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Deacetylasperulosidic acid References Information
    Citation [1]

    J Anal Methods Chem. 2013;2013:804504.

    In vivo antioxidant activity of deacetylasperulosidic Acid in noni.[Pubmed: 24371540]
    Deacetylasperulosidic acid (DAA) is a major phytochemical constituent of Morinda citrifolia (noni) fruit. Noni juice has demonstrated antioxidant activity in vivo and in human trials. To evaluate the role of Deacetylasperulosidic acid in this antioxidant activity, Wistar rats were fed 0 (control group), 15, 30, or 60 mg/kg body weight per day for 7 days. Deacetylasperulosidic acid ingestion did not influence serum glutathione peroxidase activity. These results suggest that Deacetylasperulosidic acid contributes to the antioxidant activity of noni juice by increasing superoxide dismutase activity. The fact that malondialdehyde concentrations declined with increased Deacetylasperulosidic acid dose, despite the lack of glutathione peroxidase-inducing activity, suggests that Deacetylasperulosidic acid may also increase catalase activity. It has been previously reported that noni juice increases catalase activity in vivo but additional research is required to confirm the effect of Deacetylasperulosidic acid on catalase.
    Citation [2]

    Nat Prod Commun. 2014 Apr;9(4):445-50.

    Activation of cell-mediated immunity by Morinda citrifolia fruit extract and its constituents.[Pubmed: 24868850]
    We investigated the active principles of Noni-ext and identified an iridoid glycoside, Deacetylasperulosidic acid. Oral administration of Deacetylasperulosidic acid inhibited the reduction of ear swelling, and also cancelled the suppression of IL-2 production along with the activation of natural killer cells in the same manner as that of Noni-ext.