|Source:||The herbs of Hedyotis diffusa Willd.|
|Biological Activity or Inhibitors:||1. Deacetylasperulosidic acid may increase catalase activity.
2. Deacetylasperulosidic acid inhibits the reduction of ear swelling, and also cancels the suppression of IL-2 production along with the activation of natural killer cells in the same manner as that of Noni-ext.
|Solvent:||DMSO, Pyridine, Methanol, Ethanol, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||2.5621 mL||12.8107 mL||25.6213 mL||51.2426 mL||64.0533 mL|
|5 mM||0.5124 mL||2.5621 mL||5.1243 mL||10.2485 mL||12.8107 mL|
|10 mM||0.2562 mL||1.2811 mL||2.5621 mL||5.1243 mL||6.4053 mL|
|50 mM||0.0512 mL||0.2562 mL||0.5124 mL||1.0249 mL||1.2811 mL|
|100 mM||0.0256 mL||0.1281 mL||0.2562 mL||0.5124 mL||0.6405 mL|
J Anal Methods Chem. 2013;2013:804504.
|In vivo antioxidant activity of deacetylasperulosidic Acid in noni.[Pubmed: 24371540]|
|Deacetylasperulosidic acid (DAA) is a major phytochemical constituent of Morinda citrifolia (noni) fruit. Noni juice has demonstrated antioxidant activity in vivo and in human trials. To evaluate the role of Deacetylasperulosidic acid in this antioxidant activity, Wistar rats were fed 0 (control group), 15, 30, or 60 mg/kg body weight per day for 7 days. Deacetylasperulosidic acid ingestion did not influence serum glutathione peroxidase activity. These results suggest that Deacetylasperulosidic acid contributes to the antioxidant activity of noni juice by increasing superoxide dismutase activity. The fact that malondialdehyde concentrations declined with increased Deacetylasperulosidic acid dose, despite the lack of glutathione peroxidase-inducing activity, suggests that Deacetylasperulosidic acid may also increase catalase activity. It has been previously reported that noni juice increases catalase activity in vivo but additional research is required to confirm the effect of Deacetylasperulosidic acid on catalase.|
Nat Prod Commun. 2014 Apr;9(4):445-50.
|Activation of cell-mediated immunity by Morinda citrifolia fruit extract and its constituents.[Pubmed: 24868850]|
|We investigated the active principles of Noni-ext and identified an iridoid glycoside, Deacetylasperulosidic acid. Oral administration of Deacetylasperulosidic acid inhibited the reduction of ear swelling, and also cancelled the suppression of IL-2 production along with the activation of natural killer cells in the same manner as that of Noni-ext.|